Zinc acetate explained

Zinc acetate is a salt with the formula Zn(CH3CO2)2, which commonly occurs as the dihydrate Zn(CH3CO2)2·2H2O. Both the hydrate and the anhydrous forms are colorless solids that are used as dietary supplements. When used as a food additive, it has the E number E650.

Uses

Zinc acetate is a component of some medicines, e.g., lozenges for treating the common cold.[1] Zinc acetate can also be used as a dietary supplement.[2] As an oral daily supplement it is used to inhibit the body's absorption of copper as part of the treatment for Wilson's disease.[3] Zinc acetate is also sold as an astringent in the form of an ointment, a topical lotion, or combined with an antibiotic such as erythromycin for the topical treatment of acne.[4] It is commonly sold as a topical anti-itch ointment.

Zinc acetate is used as the catalyst for the industrial production of vinyl acetate from acetylene:. Approximately 1/3 of the worlds production uses this route, which because of its environmental impact, is mainly practiced in countries with relaxed environmental regulations such as China.

Preparation

Zinc acetates are prepared by the action of acetic acid on zinc carbonate or zinc metal. Treatment of zinc nitrate with acetic anhydride is an alternative route.[5]

Structures

In anhydrous zinc acetate the zinc is coordinated to four oxygen atoms to give a tetrahedral environment, these tetrahedral polyhedra are then interconnected by acetate ligands to give a range of polymeric structures.[6] [7] [8]

In the dihydrate, zinc is octahedral, wherein both acetate groups are bidentate.[9] [10]

Reactions

Heating Zn(CH3CO2)2 in a vacuum results in a loss of acetic anhydride, leaving a residue of "basic zinc acetate," with the formula Zn4O(CH3CO2)6. It can also be prepared by a reaction of glacial acetic acid with zinc oxide.[11] The cluster compound has a tetrahedral structure with an oxide ligand at its center[12] Basic zinc acetate is a common precursor to metal-organic frameworks (MOFs).

See also

Notes and References

  1. Web site: Zinc – Fact Sheet for Health Professionals . Office of Dietary Supplements, US National Institutes of Health . February 11, 2016. November 15, 2018.
  2. 10.3945/jn.113.181487. 24259556. 3901420. Zinc Absorption by Young Adults from Supplemental Zinc Citrate is Comparable with That from Zinc Gluconate and Higher than from Zinc Oxide. The Journal of Nutrition. 144. 2. 132–136. 2014. Wegmüller. Rita. Tay. Fabian. Zeder. Christophe. Brnić. Marica. Hurrell. Richard F..
  3. Web site: November 15, 2018 . Wilson Disease . NIDDK . July 2014 . live . https://web.archive.org/web/20161004223012/https://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/wilson-disease/Pages/facts.aspx . 2016-10-04.
  4. 2138176. 1990. Schachner. L.. Topical erythromycin and zinc therapy for acne. Journal of the American Academy of Dermatology. 22. 2 Pt 1. 253–60. Eaglstein. W.. Kittles. C.. Mertz. P.. 10.1016/0190-9622(90)70034-f. free.
  5. Book: O. F. Wagenknecht. R. Juza. Zinc Acetate. Handbook of Preparative Inorganic Chemistry, 2nd Ed. . G. Brauer. Academic Press. 1963. NY, NY. 2pages=1087.
  6. Clegg. W.. Little. I. R.. Straughan. B. P.. Monoclinic anhydrous zinc(II) acetate. Acta Crystallographica Section C. 15 December 1986. 42. 12. 1701–1703. 10.1107/S010827018609087X. 1986AcCrC..42.1701C .
  7. He. Hongshan. A new monoclinic polymorph of anhydrous zinc acetate. Acta Crystallographica Section E. 15 November 2006. 62. 12. m3291–m3292. 10.1107/S1600536806046678.
  8. Capilla, A. V. . Aranda, R. A. . Anhydrous Zinc(II) Acetate (CH3-COO)2Zn . Crystal Structure Communications . 1979 . 8 . 795–797.
  9. van Niekerk. J. N.. Schoening. F. R. L.. Talbot. J. H.. The crystal structure of zinc acetate dihydrate, Zn(CH3COO)2.2H2O. Acta Crystallographica. 10 September 1953. 6. 8. 720–723. 10.1107/S0365110X53002015. free. 1953AcCry...6..720V .
  10. Ishioka. T.. Murata. A.. Kitagawa. Y.. Nakamura. K. T.. Zinc(II) Acetate Dihydrate. Acta Crystallographica Section C. 15 August 1997. 53. 8. 1029–1031. 10.1107/S0108270197004484. 1997AcCrC..53.1029I .
  11. Poshkus . Algirdas C. . Improved synthesis of basic zinc acetate, hexakis(.mu.-acetato)-.mu.-oxotetrazinc . Industrial & Engineering Chemistry Product Research and Development . June 1983 . 22 . 2 . 380–381 . 10.1021/i300010a041.
  12. Koyama, H. . Saito, Y. . The Crystal Structure of Zinc Oxyacetate, Zn4O(CH3COO)6 . . 1954 . 27 . 112–114 . 10.1246/bcsj.27.112 . 2. free .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Zinc acetate".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.