Zilebesiran Explained
Synonyms: | AD-85481, ALN-85481, ALN-AGT01 |
Legal Status: | Investigational |
Unii: | E422BH4BRK |
Cas Number: | 2380166-33-4 |
Zilebesiran is an experimental small interfering RNA developed by Roche and Alnylam that is administered subcutaneously twice annually to lower blood pressure in people already taking other antihypertensive drugs.[1] [2] [3] It works by impeding the synthesis of angiotensinogen in the liver.[4] [5]
Notes and References
- Carvalho . Thiago . RNA interference treatment targeting angiotensinogen lowers blood pressure . Nature Medicine . 29 . 12 . 2023 . 1078-8956 . 10.1038/d41591-023-00091-x . 2962–2963. 37845541 .
- Khan . Rida S. . Frishman . William H. . Zilebesiran: A Promising Antihypertensive Therapy Inhibiting Angiotensinogen Synthesis . Cardiology in Review . 22 February 2024 . 10.1097/CRD.0000000000000645. 38385680 .
- Web site: Waldron . James . 2nd win for Alnylam RNAi blood pressure med strengthens Roche's $2.8B biobucks bet . Fierce Biotech . 2024-03-05 . 2024-03-06.
- Desai . Akshay S. . Webb . David J. . Taubel . Jorg . Casey . Sarah . Cheng . Yansong . Robbie . Gabriel J. . Foster . Don . Huang . Stephen A. . Rhyee . Sean . Sweetser . Marianne T. . Bakris . George L. . Zilebesiran, an RNA Interference Therapeutic Agent for Hypertension . New England Journal of Medicine . 20 July 2023 . 389 . 3 . 228–238 . 10.1056/NEJMoa2208391. 37467498 . 20.500.11820/9ec1c393-058a-4fe7-8e8f-df207dcdfb85 . free .
- Bakris . George L. . Saxena . Manish . Gupta . Anil . Chalhoub . Fadi . Lee . Jongtae . Stiglitz . Daniel . Makarova . Nune . Goyal . Nitender . Guo . Weinong . Zappe . Dion . Desai . Akshay S. . Carr . George . Case . Christopher . Jaeger . Lauren . Bruns . Lisa . Stratman . Ginger . Kidwell . Christy . Cunningham . Suzin . Piccone . Nicholas . Klein . Mordecai . Acuna . Maria . Arora . Srishti . Clark . Amanda . Fink . Ezekiel . Garcia . Cesia . George . Astrid . Gray . Elizabeth . Mahaffey . Caroline . McElheney . Maria . Ortiz . Elizabeth . Saumya . Sunny . Wallace . Adele . Watts . Jenelle . Zambrana . Daisy . Denham . Douglas . Rivera . Erica . Avworo . Ayoade . Hedges . Parke . Fancher . Corri . Abadier . Rafik . Braud . Lisa . Cenatiempo . Laura . Elwood . Amanda . Gray . Linda . Gray . Peter . Griffin . Kimberly . Khan . Hasibul . Kongquee . Nadeen . LaTorraca . Susan . Liles . Tiffany . Livingston . Jill . Lozano . Marc . Lupton . Amy . Lyles . Tiffany . Mardini . Deana . Moss . Susan . Packer . Karen . Patel . Aakash . Russ . Tina . Scinicariello . Brianna . Trull . Shannon . Warren . Blair . Chalhoub . Fadi . Angel . Susan . Dhakhwa . Sujeeta . Gabon . Ivy . Goodwin . Leticia . Joshi Jones . Nandita . Joyce . Mark . Kamble . Niketa . McFall . Brooke . Githiiyu . Rose . Robinson . Leticia . Tomlinson . Lauren . Hadziavdic . Emir . Vega . Stephany . Greenwald . James . Achan . Jessica . Ruiz . Lucille . Buksh . Mehwish . Chauhan . Omkar . Derisseau . Elisee . Ferguson . Faith . Grabowski . Monika . Gumerova . Larisa . Hernandez . Miriam . Martin . Kenna . Patel . Krina . Nanda . Dibnain . Perez . Jose . Ribeca . Corey . Rueda . Elijah . Sordi Guth . Ana . Zaki . Nader . Green . Ebony . Mondoc . Nina . Buynak . Robert . Andree . Stephanie . Brazinsky . Martha . Fuller . Lisa . Green . Nikki . Ibrahim . Hannade . Idowu . Marilyn . Lee . Miranda . Lewis . Erica . Luna . Goldie . McNeal . Rachel . Owens . Alicia . Perez . Consuelita . Petty . Taryn . Smith . Megan . Volom . Patricia . Webb . Angela . Williams . Destiny . Yarosz . Mark . Gabra . Nashwa . Andrawis . Nabil . Aziz . Amy . Hanna . Magda . Manalo . Josefina . Helow . Victoria . Davila . William . Crisp . Sydney . Douglas . Yvonne . Everett . Jenna . Graham . Sarah . Heard . Ellen . Mackie . Michelle . Mayer . Suman . Moore . Lisa . Resurreccion . Stephanie . Sidey . Jennifer . Stephens . Michael . Strickland . Mary . Van Camp . Dawn . Wilder . Stephanie . Witt . Anne . Wolfer . Jolenne . Groben . Lucas . Aeschliman . Lindsey . Audlehelm . Emily . Fitz . Casey . Greene . Judi . Hippen . Emily . Johnson . Michelle . Latcham . Allan . Leggett . Shekela . Link . Keeta . Lovell . James . Marlow . Kourtney . Marske . Cynthia . Maxwell . Kelsey . Newsom-Henderson . Charlotte . Oelberg . Darcie . Ollinger . Kathleen . Risius . Rebecca . Ryther . Kylea . Waddell . Alyssa . Zellerman . Tyler . Albornoz Santofimio . Martin . Plantholt . Stephen . Beatty . Morgan . Blubaugh . Heather . Bootz . Tina . Cole . Jeffrey . Conners . Jasmine . Coombs . Vicki . Goddard . Chloe . Ince . Carlos . Kiddy . Gail . Klimuszka . Barbara . Kuhn . Frederick . Lowry . David . Previll . Patricia . Rioux . Stephanie . Scott . Jasmine . Shepherd . Britney . Urffer . Amy . Smiley . Sarah . Lucksinger . Gregg . Alvord . Allison . Anderson . Jordan . Block . Courtney . Chan . Ashley . Delgado . John . Frost . Kambrea . Gadbois . Levi . Hamlin . Danuel . Johnson . Sarah . Juncal . Vivianna . Kelly . Kary . Kelly . Emily . Kelly . Lilly . Kerwin . Avery . Kuehl . Audrey . Ostovar . Jaleh . Rackley . Ryan . Rocha . George . Sandberg . Lacee . Sheghewi . Sarah . Smith . Tiffany . Taucher . Ben . Vasquez . Cecilia . Villa Rodriguez . Francisca . Weisbart . Jay . Wescom . Veronica . Williams . Keenan . Overcash . Jeffrey Scott . Anorve . Angela . Asmann . Hunter . Bovee . Gordon . Castillo . Laura . Chu . Hanh . Coslet . Jordan . Davis . Allison . Dinan . Mary . Dubbula . Amanda . Esparza . Jacob . Foster . Ann . Garcia . Andrea . Gonzales . Jessica . Gonzalez . Lizette . Kappen . Pat . Kornblatt . Allison . Lauderdale . Brandon . Lee . Kia . Lindholm . Sylvia . Lindsay . Ashliegh . Llanos Gomez . Luis . Marquez . Adrienna . Meza . Catherine . Odom . Shandel . Orel . Makenna . Paselio . Shanna . Penziner . Samuel . Pu . Helen . Quillin . Kimberly . Ramirez . Cesar . Ramirez . Roxanna . Salgado . Monica . Shores . Marcy . Taitingfong . Raquel . Tande . Jennifer . Tuiletufuga . Van . Tyler . Katrina . Vega . Linda . Zepeda . Karla . Anderson . Corey . Carhill . Nikki . Clark . Benjamin . Dean . Lisa . Devine . Naomi . DiPeri . Sophia . Espinal . Gladys . Hawkins . Ronald . Irra . Gabriela . Ledezma . Angela . Lopez-Wood . Georgina . Luna . Micaela . Mansour . Wael . Marriott . Tasha . Perez . Ashley . Ramsey . James . Reedy . William . Spinks . Hannah . Tanori . Cecilia . Tatelbaum . David . Vasquez . Rudy . Vasquez . Kim . Vigil . Jori . Worthen . Isabel . Yu . Devin . Zuniga . Jessica . Dennis . Patrick . Alvarado . Lauren . Cox . Armand . Cullaro . Victoria . Dunbar . John . Giorlando . Katherine . Hannan . London . Hastings . Tyler . Hoskins . Geoff . Krambeck . Emily . Laurent . Juliana . Martinez . Olga Michelle . Mister . Reggie . Moss . Autumn . Muli . Margaret . Quinn . Nicolette . Reed . Brittany . Robinson . Adam . Saavedra . Casey . Simon . Caitlin . Smith . Derek . Touchet . Dylan . Wright . Annie . Trevino . Miguel . DeVries . Benjamin . Allison-Hicks . Sara . Light . Timothy . Rubach . Wendy . Mai . Kimberly . Osborn . Tracey . Sheets . Lori . Carver . Dusty . Reichman . Alan . Lotfi . Djamchid . Berrios . Nelson . Vulichi . Sangeetha . Naguleswaran . Tulashi . Subhan . Yvonne . Rios . Monica . Baron . Diana . Khowaja . Abdul . Nair . Siddharth . Vicente . Michael . Gonzalez Gomez . Luvia Lizette . Acevedo Gomez . Uriel Salvador . Lamichhane . Janak . Ekomoda . Efe . Nair . Akhila . Maldonado . Shana . Naqvi . Mobina . Dayani . Fahim . Patro . Sontoshi . Golandaz . LubnaGazal . Jaka . Amin . Rios . Santiago . Gurung . Maushami . Gongloor . Pratik . Coreas . David . Demir . Tarik . Celik . Zehra . McGill . Lora . Usdan . Lisa . Arnold . Valerie . Heckle . Keerthi . Scatamacchia . Carolyn . Anthony . Codi . Marsh . Carol . Fair . Jernell . Stewart . Anekeya . Hamlet . Rebecca . Presley . Robyn . Granberry . Charles . Flowers . Melissa . Houpt . Cathy . O'Brien . Debra . Evans . Kelsey . Williams . Mary . Sinatra . Julia . Powell . Irene . Flagg . Tavia . Pipkin . LaKeshia . Wheeler . Vanessa . Wells . Erin . Gruber . Brandi . Jones . Amber . Toor . Monica . Iskiwitz . Kelly . Boyd . Mia . Epps . Sharneiseca . Cole . Frank . Grayson-Mathis . Charlotte . Web . Maci . Turner . Catrina . Reese . Krystal . Robinson . Dana . Goodwin . Atira . Parker . Kyle . Ward . Chantelle . Solomon . Amber . Lawson . Taylor . Pledger . Marquita . Lane Peterson . Amanda . Carignan . Monique . Oguoma-Richards . David . Jones . Stacy . McFarland-Head . Kiara . Bundeff . Brittany . Wojtowicz . Stephanie . Holland . Cynthia . Sanders . Taylor . Simon . Lee . Lawrence . Caitlin . Bolton . Brittany . Lemoine . Kandice . Harris . Kasey . Kingsley . Hilary . Bryant . Danielle . Clawson . Korie . Murphy . Colleen . Crawford Allison . Dale . Newman . Gregory . Preece . Dedra . Zook . Pamela . Roznos . Taylor . Russell . Sharla . Rodriguez . Richard . Roy . Angela . Layle . Stacey . Mehra . Purvi . Bowen . Samantha . Johnson . Daniel . Guillen . Natalie . Leone . Sofia . McCormick . Guinevere . Hermann . Laurel . Sarno . Lerner . Abellatif . Taher . Cleghorn . Monica . Elansary . Aya . Israel . Athalyah . Leeward . Michelle . Parra . Claudia . Harris . Sydney . Patel . Prianka . Cawley . Megan . Castro . Myrna . Miroshnikova . Tatyana . Dever . Michael . Venereo . Jorge . Paez . Henry . Isla . Andres . Martin . Yailin . Fernandez . Ana . Hernandez . Isabel . Isla Lavoy . Andrew . Rios . Nancy . Hernandez . Armando . Denenberg . Michael . McTier . Treacy . Reynolds . Caroline . Thomas . Lacie . Eubanks . Connie . Oliver . Tori . Jacobs . Michael . Mirkil . Vincent . Menasche . Kathleen . Yee . Michael . Alvarado Vasquez . Bonny . Garcia . Candice . Elio . Laura . Arenas . Allan . Buena . Clarissa . Garcia . Cristina . Cannon . Michael . Novotny . Erin . Oliver . Michelle . Cannon . Amanda . Gatdula . Mark . Gillenwater . Cyn . Rafi . Adam . Derian . Wissam . Ramsey . Miranda . Culbreth . Evan . Fessler . Catherine . Sorrill . Kelly . Mauri . Monica . Rosen . Jeffrey . Acosta . Olga . Brauchle . Walter . Castaneda . Dadllany . Castells . Mailyn . Castro . Daniela . Cespedes Laplace . Maria Bibiana . Flerisme . Magdala . Garcia . Rocio . Gomez . Julio . Hidalgo . Michael . Jimenez . Gabriela . Legon . Miguel . Lella . Victoria . Lemus . Kimanys . Rico-Aramillo . Sheilla . Rodriguez . Maria . Rodriguez . Yelida . Salazar . Latisha . Santana . Carlos . Tercero . Nelly . Martin . Earl E. . Acevedo . Maria . Anderson . Amy . Baig . Talha . Baker . Rana . Basrai . Reemsha . Cabrera . Nora . Caroll . Cassidy . Chatmon . Shanika . Cheema . Sukhvinder . Chowdhry . Anum . Cordero . Nicole . Deandres . Carolina . Deshpande . Mounika . Dileep . Ambily . Dolfi . Kimberly . Eng . Lara . Fountain . Niccirria . Gali . Ramani . Hernandez . Adrienne . Iskandar . Arsani . Khan . Riaz . Knight . Adrianna . Kundapati . Soni . Lobo . Irma . Lokhandwala . Zahra . Lokhandwala . Zara . Mahmood . Faryal . Marediya . Rifa . Martin . Earl F . Melendez . Mirella . Moosa . Asfand . Motiwala . Alefiyah . Muhebb . Shamnun . Murray . Monica . Rehman . Muneeb . Rivera . Ariel . Shah . Ashay . Solorzano . Sara . Somani . Laila . Soneira . Loreta . Starr . Amy . Thompson . Danielle . Torres . Andrea . Tran . Elizabeth . Ullah . Mohammad Ali . Valentine . Allie . Vaquerano . Laura . Yake . Amanda . Yousif . Yousra . Zaldivar . Ashley . Byars . William . Brown . Hillary . Claire Gaskin . Anne . Clayton . Caitlynn . Davis . Christopher . Dillon . Sydney . Driggers . Belinda . Ferrell . Anfernee . Green . Danielle Elizabeth . Hunt . Lisa . Jeffers . Cathleen . Kirkland . Cindy . Lopez . Lina . Mayfield . Ronald . Mercer . Carole . Parsons . Kathy . Patton . Sharon . Puck . Kayla . Restrepo . Lina . Sheppard . Tanya . Teachman . Gina . Velez . Jessica . Whitehead . Amanda . Jain . Mahendra . Asanji . Gloria . Garrett . Jennifer . Gill . Katie . Hester . DeAndrea . Jain . Bela . Mitchell . Yvette . Becker . Teresa . McKeown-Biagas . Cecilia . Fragoso . Veronica . Holloway . Lisa . Kowalski . Tracy . Barr . Shakira . Colville . Bonnie . Yang . Chen-Ho . Glasper . Danitra . Phuah . Allan . Miller . Vicki . Schmidt . Sheila . Jafri . Ashraf . Sureshbabu . Waheeda . Mir . Leena . Sharma . Stuti . Asaad . Saja . Hasnain . Muhammad . Ngo . Tru . Hari . Devi . Oheri . Ikenna . Patwary . Asma . Mohamed . Mahmoud . Hernandez . Priscilla . Gioia . Jonatan . Dalal . Abdeali . Ngban . Pauline . Smith . Sandra . Martinez Leal . Bernardo . Assaf . Akram . Martinez . Alondra . Khan . Khola . Castello . Jacqueline . Potapenko . Mariya . Wahaj . Zurzar . Elmachtoub . Faris . Akhtar . Amna . Areeb Siddiqui . Muhammad . Jamal . Maira . Rizvi . Mohammad . Sainz . Karina . Lucky-Dania . Sarah . Villarreal . Stacy . Fernandez . William . Hampton . Shamarrian . Bellamy . Jerry . Brown . Lonisha . Doran . Evan . Manzanares . Eduardo . Palmer . James . Sanders . Aaron . Bokhari . Faraya . Fenuyi . Omowunmi . Greer . Clarissia . Jang . Hansol . Juanillo . Andrea . Reese . Crystal . Narla . Dheeraj . Okoko . Ijeoma . Woodham . Cara . Eaton . Rose . Khawaja . Shariqa . Mushtag . Tehreem . Nisar Bhutto . Asifa . Solorsano . Sara . Ahmed . Sajeel . Shamim . Rabia . Gonzalez . Norma . Ardoin . Felicia . Moore . Joshua . Nuncio . Nina . Ray . Eric . Sikes . Kara . Troutman . Imani . West . Natasha . Wilson . Quiana . Young . Nikisha . Baloch . Misbah . Karimjee . Najmuddin . Carroll . Kristy . Broachwala . Sakina . Calais . Natalee . Laabs . Jessica . Marler . Karen . Rizvi . Samana . Syed . Amar . Syed . Narjis . Rizvi . Zamir . Hariwala . Zohair . Gloyd . Patty . Rizvi . Abid . Marcum . Benjamin . Carswell . Joshua . Fanning . Cortney . Bull . Lesslie . Corta . Peter . James . Holly . Martinez . David . Scurlark . Robin . Elliott . Stephanie . Beck . Sydney . Beck . Cayla . Glover . Sarah . Bonson . Jasmine . Patel . Tanisha . Matthew . Garrett . Davidoff . Kyla . Vesely . Jim . Horton . Cyrus . Barbour . Rebecca . Pereira . Isabel . Rivero . Gina . Alston . Denise . Miller . Paulina . Downing . Frances . Sanchez Crespo . Nelia . Schwartz . Howard . Mederos . Surisaday . Tamayo . Janet Sentil . Shapiro . Craig . Mallet . Orbein . Plotka . Karenda . Valladares . Carlos . Palmer . Karenda . Deltejo . Dayana . Garcia . Katherine . Camacho . Marilein . Chanza . Yarixa . Morera . Jocelyn . Davis . Claudette . Dawson . Karlene . Rosales . Vivian . Torres . Dunia . Pinero . Maria . Cruz . Catherine . Rivera . Beatriz . Balebona . Patricia . Basurco . Andrea . Montoya . Jenny . Yaniz . Mikael . Petit Phar . Pedro . Filgueiras . Christy . Fernandez . May . Skrine . Latauri . Alcantara . Aaliarys . Parodis . Isnier . Parodis . Jessica . Jara . Jailene . Alouption . Joslandey . Yan . Malvin . Padilla . Jesse . Cruz . Carolina . Bran . Bianca . Flores . Vanessa . Perez . Leandro . Labovitz . Arthur . Roth . Tracey . Javier . Julian . Jimenez . Lorenzo . Ojeda . Carmen . Caceres . Maria . Misir . Caren . Rudd . Kyle . Ramos . Juan . Deeb . Wasim . Bisharat . Mohannad . Dennis-Saltz . Amy . Sutton . David . Magee . James . Ashchi . Majdi . Goldfaden . Rebecca . Sheikh-Ali . Mae . Kelly . Stacey . Nicolas Saikali . Elias . Rodel Ramirez . Gloria . Domingo . Debbie . Hodge . William . Greenewalt . Adrienne . Stamschror . Lauren . Preston . Kaitlyn . Petschonek . Leann . Graf . Katie . Sutton . Lynsey . Edson . Meghan . Charron . Madison . Taylor . Mika . Knisely . Emily . Gore . Ashwini . Jones . Thomas . Johns . Barry . Sheldon . Jennifer . Merritt . Kayla . Hichkad . Lisa . Barbee . Leah . Riley . Amanda . Alexander . Lindsay . Dasher . Lilly . Torres Lopez . Elio Argimiro . Baez Bonilla . Rafael . Loza . Anibal . Hernandez . Dunia . Perez . Yaili . Perez . Alejandro . Perez . Yalily . Medina . Denisse . Mantero . Emilio . Vega . Ramses . Pedraza . Noel . Sosa . Damian . Robles . Lys . Machado . Yennifer . Sosa . Yoandra . Guzman . David . Grio . Maricor . Frias . Juan . Kelly . Sharon . Leibowitz . Mark . Nelson . John . Handy . Cheryll . Greenberg . Alina . Vega . Norma . Francisco . Angelica . Soto . Coralia . Arcadia . Sinthia . Francisco . Eulalia . Escareno . Nicol . Ayala . Nelly . Muniz . Jennifer . Espino . Jose . Vargas . Daniel . Jimenez . Rosie . Lopez . Stephanie . Gallaga . Iliana . Heredia . Genesis . Barranco Santana . Elizabeth . Mendoza-Rodriguez . Rafael . Cancel Santana . Sara . Román . Alejandra . Arroyo Torres . Irmaris . Franceschini . Velma . Garcia . Brenda . Jimenez . Nancy . Irizarry Ortiz . Michele . Torres Antommattei . Armando . Comulada-Rivera . Angel . Pintado . Andrea . Ortiz . Sonia . Rodriguez . Adamaris . Mojica Ramirez . Rosa . Olofintuyi . Anthony . Alvarez . Ricardo . Pitts . Jay . Samraj . Jackelyn . Vasbinder . Alma . Averett . Amaya . Kane . Thomas . Farley . Harlicia . Kendall . Thomas . Kemmerlin . Richard . Saunders . Jackie . Livingston . Yolanda . McLean . Barry . Mayer . Maureen . Goodwin . Valerie . Ngugi . Evelyne . Mishra . Prateek . Carter . Hannah . Szymela . Lorie . Imran . Ali . Abdallah . Saiaf . Clarke . Nadia . Hernandez Latog . Sylvania . Moore . Broderick . Lopez . Miguel . Tagsip . Maureen . Nepali . Prakash . Kumaran . Nivi . Jacinto . Greta . Magsino . Catherine . Batalla . Freddie . Imran . Feroza . Montgomery . Richard . Riggs . Stephanie . Haamid . Shavonna . Whitt . Catherine . Hopper . William . Smith . Dominique . Kordsmeier . Julia . Sherron . Courtney . Plummer . Miyah . Jimenez . Sherisse . Newkirk . Airelle . Murray . Laura . Scott . Haley . Whitney . Rebecca . Castro . Monica . Rhames . Michelle . Cortes-Maisonet . Gregorio . Miranda Martinez . Luis . Allende-Vigo . Myriam . Vila . Karina . Santiago Rivera . Michelle . Yunker . Valerie . Rivera . Bryan . Rodriguez . Alex . Rivera . Carla . Reyes Blanco . Genesis . Batista Colon . Keven . Cruz . Mariely . Nweke . Chinedu . Okafor . Norah . Nweke . Angela . Chaves-Montoya . Daisy . Patrick . Heather . Alvarez . Stephanie . Momeh . Eunice . Anaele . Cyriacus . McArthur . Katherine . Longonje . Peter . Husbands . Danielle . Williams . Iasia . Dillingham . Christine . Sanchez Sayyah . Gloria . Carey . Laura . Brock . Clarissa . Hussain . Rubaba . Sultana . Khadiza . Mohammad . Omar . Lopez . Jennifer . Bittencourt . Valeria . Prasad . Sneha . Akther . Nafsun . Smith . Timothy . Rocco . Sheri . Straatmann . Donna . Stoneman . Jill . Maryas . Elizabeth . Gravier . Johanna . Faggett . Walter . Jimenez . Andres . Maya Alvarez . Maria . Evora . Wendy . Herrera . Alcira . Leonardi . Lorena . Karns . Adam . Sisneros . Edith . Hong . Sarom . Rudyk . Iurii . Medentseva . Olena . Alexeeva . Maryna . Strakhova . Nataliya . Lozyk . Tetyana . Babichev . Denys . Yushko . Kostiantyn . Tseluyko . Vira . Zhadan . Andriy . Butko . Olena . Mishchenko . Oksana . Radchenko . Olha . Karpenko . Oleksandr . Klimko . Polina . Berezhniak . Anna . Todoriuk . Liudmyla . Bezuglova . Svitlana . Mitskevych . Liubov . Kizim . Svitlana . Nevolina . Inna . Galchenko . Oksana . Korzh . Oleksii . Pankova . Olena . Fylenko . Yana . Ziabchenko . Valeriia . Krasnokutskiy . Sergiy . Liashok . Artem . Donets . Oleksandra . Mishustina . Anna . Khrustalyova . Liliya . Donets . Dmytro . Rybachok . Yuliia . Senchylo . Vyacheslav . Lyakhova . Iryna . Takhaieva . Olena . Shkroba . Anna . Shchypak . Diana . Tryshchuk . Nadiya . Pieshkova . Olga . Karaia . Olena . Yakovleva . Anna . Horoshko . Olha . Lohdanidi . Tetiana . Belei . Nestor . Kuzmenko . Inga . Demchuk . Tetiana . Cherniuk . Sergii . Kozliuk . Alina . Kovalenko . Volodymyr . Adarichev . Valerii . Vakaliuk . Igor . Tymochko . Nataliia . Sovtus . Volodymyra . Haliuk . Nadiia . Gaudet . Daniel . Côté . Fanny . Milot . Jean-Philippe . Roy . Nathalie . Larouche . Andrea . Piché . Johanne . Charest . Laurie-Anne . Dufour . Josiane . Pageau . Joannie . Audet-Verreault . Noemie . Côté . Lyne . Gagnon . Melissa . Côté . Véronique . Morin . Denise . Fortin-Mimeault . Jessica . Brassard . Marc-Olivier . Gagne . Helene . Rousseau . Sophie . Sia . Ying Tung . Guzzetti . Ezequiel . Alejandro Gisbert . Ramon . Dias . Mariana . De Oliveira . Mariana . Cote . Claudia . Rodrigues . Izabel . Blanchard . Johanne . Labbe . Laurence . Dumoulin Lemay . Sabrina . Beauchemin . Kathleen . Turcotte . Roxanne . Beaudoin . Annabelle . Saliphod . Chansamone . Lamontagne . Chantal . Trudel . Josiane . Beaudoin . Carolyne . Blanchard . Josée . Larouche . Annie . Robinaud . Cecile . Paré . Valérie . Bergeron . Alexandre . Bilodeau . Maude . Bellavance . Ethel . Betit . Eve . Fortier . Karine . Racine . Josee . Perras . Dinah . Boulanger . Elyse . Beauchesne . Christelle . Lehoux . Sarah . Turgeon . Vickie . Cote . Rachele . Tardif . Marie-Eve . Aggarwal . Naresh . Aggarwal . Puja . Patel . Bharti . Dhaliwal . Gurdeep . Aggarwal . Preeti . Tellier . Guy . Gagne . Gilbert . Laperriere . Luc . Shalala . Jennifer . Danchuk . Janelle . Barrette . Catherine . Lauzon . Lydia . Langille . Natalie . Gagné . Sarah . Lupien . Joanie . Brochu . Raphael . Coallier . Sophie . Vaillancourt . Catherine . Lachance . Pierre . Carbonneau . Diane . Thibault . Helene . Bouchard . Luc . St-Cyr . Andreanne . Rioux . Johanne . Quenneville . Laureanne . Gagnon . Constance . Nony . Theana . Laberge . Pascale . Corbin . Annabelle . Patry . Isabelle . Savage . Sophie . MacNeil . Melanie . Murdock . Andrea . Inglis . Jill . Libbus . Katelyn . Smith . Kathryn . Johnson . Deseray . Walters-Findlay . Linda . Harris . Laura . Hutchison . Taylor . Rafuse . Autumn . Thorsen . Julie . MacDonald . Greg . Akhras . Ronald . Assef . Richard . Irani . Elise . Khayat . Rania . Guidolin . Scott . Gupta . Anil . Price . David . Gandhi . Amisha . Chhabra . Ajay . Gandhi . Bhavya . Acharya . Shrey . Panchal . Maheshwari . Kansal . Bindu . Bailey . Gordon . Harvalik . Paula . Demchuk . Kerri . Saxena . Manish . Collier . David . David . Colvell . Quiros . Benildo Jr . Patel . Mital . Balawon . Armida . Galera . Francis . Michalska . Ania . Piniera . Brian . Uddin . Rahat . Abbott . Joanna . Faulkner . Karen . Yousef . Tamer . Love . Kyle . Zagdanski . Ariella . Slaney . Susan . Anderson . Michelle . Leath . Aimee . Dunlop . Cheryl . Hardy . Elizabeth . Wall . Shannon . El-Koubani . Osman . Kelt . Tracy . Connolly . Billy-Jean . Marmion . Cheryl . Alapati . Maheswari . Simmons . Louise . Colquhoun . Caroline . Clyde . Darren . Mooty . Adrian . Mullen . Nicole . Viljoen . Marianne . Trevor . Lucy . Pretswell . Carol . Austin . Catherine . Munthali . Chigomezgo . Munsoor . Imrozia . Venkate Gowda . Madhu . Ozunlu . Pembe . Keighley . Peter . Jones . Alison . James . Annette . Pollitt . Joanne . Littlewood . Wendy . Al-Sheikhly . Lena . Lee . David . Nistor . Denise . Roberts . Elaine . Mawdsley . Gayle . Sobolewska . Kamila . Hannis . Katrina . Wojtkiewicz . Klaudia . Stopford . Lauren . Halliwell . Lindsay . Mort . Veronica . McGrath . Victoria . Osborne . Harry . Merrick . Alison . Basikolo . Cathrine . Ghysels . Inge . Fenlon . Laura . Beech . Lucy . Munoz . Olga Lusquinos . Bilton . Sarah . Goddard . Lyne . Gillon . Tracey . Taylor . Stacy . Tyson . Brianne . Connor . Victoria . Felber . Hannah . Fallows . Angela . Clowes . Jacqueline . Cheung . Shirley . RNA Interference With Zilebesiran for Mild to Moderate Hypertension: The KARDIA-1 Randomized Clinical Trial . JAMA . 5 March 2024 . 331 . 9 . 740–749 . 10.1001/jama.2024.0728. 38363577 . 10873804 . August 16, 2024 .