Zhankuic acid explained

Zhankuic acids are sterols isolated from the fungus Taiwanofungus camphoratus.^[1] Zhankuic acid C possesses in vitro anti-inflammatory properties due to its role as a selective TLR4/MD-2 antagonist.^[2]

External links

• Zhankuic acid A - PubChem
• Zhankuic acid A - ChemSpider
• Zhankuic acid B - PubChem
• Zhankuic acid B - ChemSpider
• Zhankuic acid C - PubChem
• Zhankuic acid C - ChemSpider
• Antileukemia component, dehydroeburicoic acid from Antrodia camphorata induces DNA damage and apoptosis in vitro and in vivo models

Notes and References

1. Immunosuppressive effect of zhankuic acid C from Taiwanofungus camphoratus on dendritic cell activation and the contact hypersensitivity response. Bioorganic & Medicinal Chemistry Letters. 25. 20. 4637–4641. 10.1016/j.bmcl.2015.08.038. 26338360. 2015. Lin. Ming-Kuem. Lee. Meng-Shiou. Chang. Wen-Te. Chen. Hsing-Yu. Chen. Jin-Fu. Li. Yi-Rong. Lin. Chi-Chen. Wu. Tian-Shung.
2. Zhankuic Acid A Isolated from Taiwanofungus camphoratus Is a Novel Selective TLR4/MD-2 Antagonist with Anti-Inflammatory Properties. The Journal of Immunology. 192. 6. 2778–2786. 10.4049/jimmunol.1301931. 24532584. 3948111. 2014. Chen. Y.-F. Shiau. A.-L. Wang. S.-H. Yang. J.-S. Chang. S.-J. Wu. C.-L. Wu. T.-S.