Xylosyltransferase Explained

Xylosyltransferase are transferase enzymes which act upon xylose and are classified under EC 2.4.2.^{[1] [2]}

More specifically, they can refer to:

• Dolichyl-phosphate D-xylosyltransferase
• Dolichyl-xylosyl-phosphate-protein xylosyltransferase
• Flavonol-3-O-glycoside xylosyltransferase
• Glycoprotein 2-beta-D-xylosyltransferase
• Protein xylosyltransferase
• Xyloglucan 6-xylosyltransferase
• XYLT1
• XYLT2
• Zeatin O-beta-D-xylosyltransferase

References

xylosyl transferase is the first enzyme involved in the biosynthesis of glycosaminoglycan chains, an important constituent of proteoglycans. There are two types of xylosyl transferases type I and type II.

Notes and References

1. Götting . Christian . Kuhn . Joachim . Weilke . Christian . Brinkmann . Thomas . Kleesiek . Knut . Sollberg . Stephan . Huerkamp . Christina . Krieg . Thomas . June 1999 . Serum Xylosyltransferase: a New Biochemical Marker of the Sclerotic Process in Systemic Sclerosis . Journal of Investigative Dermatology . 112 . 6 . 919–924 . 10.1046/j.1523-1747.1999.00590.x . 0022-202X. free .
2. Poönighaus . Claudia . Ambrosius . Michael . Casanova . Javier Carrera . Prante . Christian . Kuhn . Joachim . Esko . Jeffrey D. . Kleesiek . Knut . Goötting . Christian . February 2007 . Human Xylosyltransferase II Is Involved in the Biosynthesis of the Uniform Tetrasaccharide Linkage Region in Chondroitin Sulfate and Heparan Sulfate Proteoglycans . Journal of Biological Chemistry . 282 . 8 . 5201–5206 . 10.1074/jbc.m611665200 . 0021-9258. free .