Omega-hydroxydecanoate dehydrogenase explained

omega-hydroxydecanoate dehydrogenase
Ec Number:	1.1.1.66
Cas Number:	9028-65-3
Go Code:	0050153

In enzymology, an omega-hydroxydecanoate dehydrogenase is an enzyme that catalyzes the chemical reaction

10-hydroxydecanoate + NAD⁺ ⇌ 10-oxodecanoate + NADH + H⁺

Thus, the two substrates of this enzyme are 10-hydroxydecanoate and NAD⁺, whereas its 3 products are 10-oxodecanoate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is 10-hydroxydecanoate:NAD⁺ 10-oxidoreductase.

References

• Kamei S, Wakabayashi K, Shimazono M . 1964 . Studies on ω-Oxidation of Fatty Acids in vitro: II. ω-Hydroxy Fatty Acid: NAD Oxidoreductase . J. Biochem. . 72–76 . 14202238 . 56.
• Mitz MA . Henrikson RL . 1961 . Omega hydroxy fatty acid dehydrogenase . Biochim. Biophys. Acta . 46 . 45–50 . 10.1016/0006-3002(61)90644-8 . 13771448 .