Vernolepin Explained

Vernolepin is a sesquiterpene lactone isolated from the dried fruit of Vernonia amygdalina. It shows platelet anti-aggregating properties^[1] and is also an irreversible DNA polymerase inhibitor,^[2] hence may have antitumor properties.

Notes and References

1. Laekeman. G. M.. Clerck, F. . Vlietinck, A. J. . Herman, A. G. . Vernolepin: An antiplatelet compound of natural origin. Naunyn-Schmiedeberg's Archives of Pharmacology. 1 January 1985. 331. 1. 108–113. 10.1007/BF00498859. 3934564. 10373287.
2. Book: Clayden, Jonathan. Organic chemistry. 2005. Oxford Univ. Press. Oxford [u.a.]. 978-0-19-850346-0. 238. Reprinted (with corrections).. registration.