Vermistatin Explained

Vermistatin is an organic compound and a metabolite of mine-dwelling Penicillium vermiculatum found in Berkeley Pit Lake, Butte, Montana.[1] Penisimplicissin is a vermistatin analog with anticancer activity.[2]

Notes and References

  1. 3793630 . 1986 . Fuska . J . Uhrín . D . Proksa . B . Votický . Z . Ruppeldt . J . The structure of vermistatin, a new metabolite from Penicillium vermiculatum . 39 . 11 . 1605–8 . The Journal of Antibiotics . 10.7164/antibiotics.39.1605. free .
  2. Stierle AA, Stierle DB, Girtsman T . Caspase-1 inhibitors from an extremophilic fungus that target specific leukemia cell lines. . J Nat Prod . 2012 . 75 . 3 . 344–50 . 22295871 . 10.1021/np200414c . 3330824 .

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