Venombin AB explained

Venombin AB
Ec Number:3.4.21.55
Cas Number:104003-74-9

Venombin AB (gabonase, okinaxobin II, Bitis gabonica venom serine proteinase, afaâ, cytin) is an enzyme.[1] This enzyme catalyses the following chemical reaction

Selective cleavage at Arg- bonds in fibrinogen to form fibrin and release fibrinopeptides A and B

This enzyme is isolated from the venom of the Gaboon viper Bitis gabonica.

Notes and References

  1. Pirkle H, Theodor I, Miyada D, Simmons G . Thrombin-like enzyme from the venom of Bitis gabonica. Purification, properties, and coagulant actions . The Journal of Biological Chemistry . 261 . 19 . 8830–5 . July 1986 . 3522580 .