Vanadocyte Explained

A vanadocyte is a specialized type of blood cell found in ascidians (tunicates). These cells are notable for their high levels of vanadium (concentrations 107 higher than that of seawater), which is typically a metabolic poison in other contexts.[1] [2]

Structure and description

Vanadocytes are specialized blood cells found in marine tunicates. These cells are 8-13 μm in size and the cytoplasm contains many acidic globules, termed "vanadophores".[3] These cells are one of several types found in the ascidian circulatory system and are abundant in the blood.[2] [1]

The cells are described as highly distinctive, with little variation between species. They have a circular outline that decays into a rosette form upon desiccation, with several inclusions that almost entirely fill the cell. The cell has a greenish color, varying from dark apple to scarcely perceptible, due to their vanadium complexes.[4] [5]

These green cells are not, as was initially believed, symbiotic zooxanthellae, although ascidians are known to have such symbiotes elsewhere.[5]

Chemistry

Vanadocytes are of interest to biologists and chemists because they contain high levels of vanadium and vacuole of sulfuric acid with acid mass fraction as high as 9 wt%, both of which are typically toxic to living creatures.[5] Additionally, the vanadium complex itself is unstable, found almost exclusively in the air-oxidizable, +3 oxidation state.[4]

Function

The function of vanadocytes is still unclear.[1] It has been proposed that the vanadocyte transports and processes nutrients, contributes to the polysaccharide external tunic, or serves as a defense mechanism. It is unlikely that the vanadium complex serves as an oxygen transport mechanism because it is unable to reversibly bind oxygen.[4]

Research into their utility as anti-biofouling (allelopathic) mechanisms concluded that the high acidity and high vanadium levels function to significantly reduce epizoic recruitment and predation.[6] [7]

Notes and References

  1. Michibata . Hitoshi . Uyama . Taro . Ueki . Tatsuya . Kanamori . Kan . Vanadocytes, cells hold the key to resolving the highly selective accumulation and reduction of vanadium in ascidians . Microscopy Research and Technique . 15 March 2002 . 56 . 6 . 421–434 . 10.1002/jemt.10042. 11921344 . 15127292 .
  2. STOECKER . DIANE . Resistance of a Tunicate to Fouling . The Biological Bulletin . December 1978 . 155 . 3 . 615–626 . 10.2307/1540795. 1540795 .
  3. Botte . L. . Scippa . S. . de Vincentiis . M. . Ultrastructural localization of vanadium in the blood cells of Ascidiacea . Experientia . September 1979 . 35 . 9 . 1228–1230 . 10.1007/BF01963306. 488290 . 33061777 .
  4. Carlson . Robert . Nuclear Magnetic Resonance Spectrum of Living Tunicate Blood Cells and the Structure of the Native Vanadium Chromogen . PNAS . 1975 . 72 . 6 . 2217–2221 . 432728 . 64680 . 1056026 . 10.1073/pnas.72.6.2217 . 1975PNAS...72.2217C . free .
  5. Webb . D.A. . Observations on the blood of certain ascidians, with special reference to the biochemistry of vanadium . Journal of Experimental Biology . 1939 . 16 . 4 . 499–523 . 10.1242/jeb.16.4.499 . 24 June 2019. free .
  6. Stoecker . Diane . Relationships between chemical defense and ecology in benthic ascidians . Marine Ecology Progress Series . 1980 . 3 . 257–265. 10.3354/meps003257 . 1980MEPS....3..257S . free .
  7. Stoecker . Diane . Distribution of acid and vanadium in Rhopalaea birkelandi tokioka . Journal of Experimental Marine Biology and Ecology . 1980 . 48 . 3 . 277–281. 10.1016/0022-0981(80)90082-9 .