Valine decarboxylase explained

valine decarboxylase
Ec Number:	4.1.1.14
Cas Number:	9031-16-7
Go Code:	0050390

In enzymology, a valine decarboxylase is an enzyme that catalyzes the chemical reaction

L-valine

\rightleftharpoons 2-methylpropanamine + CO₂

Hence, this enzyme has one substrate, L-valine, and two products, 2-methylpropanamine and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is L-valine carboxy-lyase (2-methylpropanamine-forming). Other names in common use include leucine decarboxylase and L-valine carboxy-lyase. It employs one cofactor, pyridoxal phosphate.

References

• Sutton CR, King HK . Inhibition of leucine decarboxylase by thiol-binding reagents . Archives of Biochemistry and Biophysics . 96 . 2 . 360–70 . February 1962 . 13918558 . 10.1016/0003-9861(62)90421-6 .