Undecaprenyl-diphosphooligosaccharide-protein glycotransferase explained

Undecaprenyl-diphosphooligosaccharide-protein glycotransferase
Ec Number:2.4.99.19

Undecaprenyl-diphosphooligosaccharide-protein glycotransferase (PglB) is an enzyme with systematic name .[1] [2] This enzyme catalyses the following chemical reaction

+ [protein]-L-asparagine

\rightleftharpoons

+ a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to protein L-asparagine

This is a bacterial enzyme that is isolated from Campylobacter jejuni and Campylobacter lari.

Notes and References

  1. Maita N, Nyirenda J, Igura M, Kamishikiryo J, Kohda D . Comparative structural biology of eubacterial and archaeal oligosaccharyltransferases . The Journal of Biological Chemistry . 285 . 7 . 4941–50 . February 2010 . 20007322 . 2836098 . 10.1074/jbc.M109.081752 . free .
  2. Lizak C, Gerber S, Numao S, Aebi M, Locher KP . X-ray structure of a bacterial oligosaccharyltransferase . Nature . 474 . 7351 . 350–5 . June 2011 . 21677752 . 10.1038/nature10151 . 205225231 .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Undecaprenyl-diphosphooligosaccharide-protein glycotransferase".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.