Turmerone Explained

Turmerones are a group of related chemical compounds of the sesquiterpene class. They are found in turmeric (Curcuma longa),^[1] from which they derive their name, as well as other related plants such as Curcuma caesia.^[2] There are multiple structural types of turmerones which differ in the number and placement of double bonds including α-tumerone, β-turmerone (also known as curlone), and ar-turmerone. Each of these types consists of multiple stereoisomers.

A number of in vitro biological activities of turmerones have been reported, including antiinflammatory, immunomodulatory, antiproliferative, and antifungal activities.^{[3] [4] [5]}

Notes and References

1. 10.1016/j.indcrop.2017.10.035 . Phytochemical profiles and bioactivities of essential oils extracted from seven Curcuma herbs . 2018 . Xiang . Hongping . Zhang . Lanyue . Xi . Lu . Yang . Yan . Wang . Xiaowei . Lei . Dehua . Zheng . Xi . Liu . Xiaoxuan . Industrial Crops and Products . 111 . 298–305 .
2. 10.3390/nu10091196 . free . Chemical Composition and Biological Activities of Essential Oils of Curcuma Species . 2018 . Dosoky . Noura . Setzer . William . Nutrients . 10 . 9 . 1196 . 30200410 . 6164907 .
3. 10.1038/s41598-022-15168-9 . Inhaled turmerones can be incorporated in the organs via pathways different from oral administration and can affect weight-gain of mice . 2022 . Takemoto . Yuki . Kishi . Chihiro . Ehira . Hinano . Matsui . Nobutaka . Yamaguchi . Taichi . Yoshioka . Yuri . Matsumura . Shinichi . Moriyama . Tatsuya . Zaima . Nobuhiro . Scientific Reports . 12 . 1 . 11039 . 35773461 . 9247068 . 2022NatSR..1211039T .
4. Book: 10.1016/B978-0-12-822448-9.00006-6 . Health benefits of turmeric: Emphasis on anticancer activity . Turmeric and Curcumin for Neurodegenerative Diseases . 2021 . Obulesu . Magisetty . 3–18 . 9780128224489 . 234175081 .
5. 10.4103/0253-7613.84961 . An evaluation of antioxidant, anti-inflammatory, and antinociceptive activities of essential oil from Curcuma longa. L . 2011 . Kuttan . Ramadasan . Liju . Vijayastelterb . Jeena . Kottarapat . Indian Journal of Pharmacology . 43 . 5 . 526–531 . 22021994 . 3195121 . free .