Turkesterone Explained

Drug Name:Turkesterone
C:27
H:44
O:8
Iupac Name:(2S,3R,5R,9R,10R,11R,13R,14S,17S)-2,3,11,14-tetrahydroxy-10,13-dimethyl-17-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one
Cas Number:41451-87-0
Chembl:2087140
Chemspiderid:10232962
Pubchem:14376672
Unii:53E6Z3F8ZG
Smiles:C[C@]12C[C@H]([C@H]3C(=CC(=O)[C@H]4[C@@]3(C[C@@H]([C@@H](C4)O)O)C)[C@@]1(CC[C@@H]2[C@](C)([C@@H](CCC(C)(C)O)O)O)O)O
Stdinchi:1S/C27H44O8/c1-23(2,33)8-7-21(32)26(5,34)20-6-9-27(35)15-11-16(28)14-10-17(29)18(30)12-24(14,3)22(15)19(31)13-25(20,27)4/h11,14,17-22,29-35H,6-10,12-13H2,1-5H3/t14-,17+,18-,19+,20-,21+,22+,24-,25+,26+,27+/m0/s1
Stdinchikey:WSBAGDDNVWTLOM-XHZKDPLLSA-N

Turkesterone is a phytoecdysteroid found in numerous plant species, including Ajuga turkestanica,[1] various Vitex species,[2] [3] [4] Triticum aestivum,[5] and Rhaponticum acaule.[6]

See also

Notes and References

  1. Guibout L, Mamadalieva N, Balducci C, Girault JP, Lafont R . The minor ecdysteroids from Ajuga turkestanica . Phytochemical Analysis . 2015 . 26 . 5 . 293–300 . 25953625 . 10.1002/pca.2563 . 2015PChAn..26..293G . 10373609 .
  2. dos Santos TC, Delle Monache F, Leitão SG . Ecdysteroids from two Brazilian Vitex species . Fitoterapia . 72 . 3 . 215–220 . March 2001 . 11295296 . 10.1016/s0367-326x(00)00304-x .
  3. Suksamrarn A, Kumpun S, Yingyongnarongkul BE . Ecdysteroids of Vitex scabra stem bark . Journal of Natural Products . 65 . 11 . 1690–1692 . November 2002 . 12444704 . 10.1021/np020199o .
  4. Bunu MI, Ndinteh DT, Macdonald JR, Langat MK, Isyaka SM, Sadgrove NJ, Melnikovova I, Fernandez-Cusimamani E . 6 . Ecdysteroids from the Stem Bark of Vitex doniana Sweet (Lamiaceae; ex. Verbenaceae): A Geographically Variable African Medicinal Species . Antibiotics . 10 . 8 . August 2021 . 937 . 34438987 . 10.3390/antibiotics10080937 . 8388959 . free .
  5. Janeczko A, Oklestkova J, Tarkowská D, Drygaś B . Naturally Occurring Ecdysteroids in Triticum aestivum L. and Evaluation of Fenarimol as a Potential Inhibitor of Their Biosynthesis in Plants . International Journal of Molecular Sciences . 22 . 6 . March 2021 . 2855 . 33799719 . 10.3390/ijms22062855 . 7999220 . free .
  6. Zughdani M, Yusufoğlu HS, Ekiz G, Linden A, Çalış İ . Ecdysteroids from the underground parts of Rhaponticum acaule (L.) DC . Phytochemistry . 180 . 112530 . December 2020 . 33049649 . 10.1016/j.phytochem.2020.112530 . 2020PChem.180k2530Z . 222353903 .