Tufted angioma explained

Tufted angioma
Synonyms:Acquired tufted angioma, angioblastoma, angioblastoma of Nakagawa, hypertrophic hemangioma, progressive capillary hemangioma, and tufted hemangioma.
Field:Dermatology

A tufted angioma, also known as an acquired tufted angioma, angioblastoma, angioblastoma of Nakagawa, hypertrophic hemangioma, progressive capillary hemangioma, and tufted hemangioma[1] usually develops in infancy or early childhood on the neck and upper trunk, and is an ill-defined, dull red macule with a mottled appearance, varying from 2 to 5 cm in diameter.[2]

Signs and symptoms

Tufted angioma is defined as a single tumor in the skin of the neck, upper trunk, or extremities that appears erythematous, macula, or plaque-like.[3] Common accompanying symptoms include soreness and pain, and hyperhidrosis is a common finding that affects 30% of individuals.[4] The size ranges from one centimeter to ten centimeters.[5]

Causes

Although tufted angioma can be acquired or congenital, the lesion often manifests within the first year of life in about 50% of cases.[6] Although its pathophysiology is unknown, its angiogenesis, which permits the formation of capillary lobes, is facilitated by an increase in endothelial and vascular growth factors.[7] Some writers link this illness to endocrine triggers, such as the bursts of hormones that accompany puberty, and speculate that it might be a result of reactive vascular proliferation brought on by hormonal stimulation.[8] One possible contributing factor is trauma.[9] A few cases that resolve after birth have been reported in pregnancy, including some cases that follow a familial pattern.[6]

Diagnosis

Imaging techniques such as magnetic resonance or ultrasound can be used to evaluate the affected area, distinguish one tumor from another, or both.[7] In the histopathology of tufted angioma, many lobules of tufts with a "cannonball" look are dispersed throughout the dermis, and crescent-shaped gaps are seen around the vascular tufts and in the tumor stroma.[3] [10] [11] In addition to CD31 and CD34, immunohistochemistry can be significantly positive for EN4 and Ulex uropaeus I lectin. It is sporadically positive for smooth muscle actin and negatively stained for GLUT.[11] [7]

Differential diagnosis includes congenital hemangioma, vascular malformations, infantile hemangioma, pyogenic granuloma and, in adults, kaposiform hemangioendothelioma and Kaposi sarcoma.[6]

Treatment

The majority of the time, total lesion excision is used to treat tufted angioma. Moreover, other writers have previously employed additional techniques such as cryotherapy, laser, compression treatment, surgery, interferon, topical or systemic corticosteroids, and chemotherapy.[3]

See also

Further reading

External links

Notes and References

  1. Book: Rapini, Ronald P. . Bolognia, Jean L. . Jorizzo, Joseph L. . Dermatology: 2-Volume Set . Mosby . St. Louis . 2007 . 1779 . 978-1-4160-2999-1 .
  2. James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. .
  3. da Silva . Alessandra Dutra . Ramos . Grasieli de Oliveira . Gomes . Rita Fabiane Teixeira . Martins . Marco Antônio Trevizani . Lamers . Marcelo Lazzaron . Santa’Ana Filho . Manoel . Rados . Pantelis Varvaki . Hildebrand . Laura de Campos . Visioli . Fernanda . Tufted Angioma in Children: Report of Two Cases and a Review of the Literature . Case Reports in Dentistry . Hindawi Limited . 2014 . 2014 . 2090-6447 . 10.1155/2014/942489 . free . 1–4. 25436158 . 4236965 .
  4. Wong . Su-Ni . Tay . Yong-Kwang . Tufted Angioma: A Report of Five Cases . Pediatric Dermatology . Wiley . 19 . 5 . 2002 . 0736-8046 . 10.1046/j.1525-1470.2002.00112.x . 388–393. 12383093 .
  5. Web site: UpToDate . UpToDate . 2024-05-07.
  6. Prasuna . Aeerabolli . Rao . PotharajuNarasimha . A tufted angioma . Indian Dermatology Online Journal . Medknow . 6 . 4 . 2015 . 2229-5178 . 10.4103/2229-5178.160259 . free . 266. 4513407 .
  7. Victoria Martínez . A.M. . Cubells Sánchez . L. . Esteve Martínez . A. . Estela Cubells . J.R. . Febrer Bosch . I. . Alegre de Miquel . V. . Oliver Martínez . V. . Angiomas en penacho en la infancia. Serie de 9 casos y revisión de la literatura . Anales de Pediatría . Elsevier BV . 83 . 3 . 2015 . 1695-4033 . 10.1016/j.anpedi.2014.10.018 . 201–208 . 25468452 . es.
  8. Padilla . R. Steven . Orkin . Milton . Rosai . Juan . Acquired "Tufted" Angioma (Progressive Capillary Hemangioma) . The American Journal of Dermatopathology . Ovid Technologies (Wolters Kluwer Health) . 9 . 4 . 1987 . 0193-1091 . 10.1097/00000372-198708000-00002 . 292–300.
  9. Silva . Camila Mendes da . Schettini . Antonio Pedro Mendes . Santos . Monica . Chirano . Carlos Alberto Rodrigues . Tufted angioma . Anais Brasileiros de Dermatologia . FapUNIFESP (SciELO) . 92 . 5 . 2017 . 0365-0596 . 10.1590/abd1806-4841.20175896 . 742–743. 29166525 . 5674719 .
  10. Pires . Carla Andréa Avelar . Sousa . Brena Andrade de . Amin . Gabriela Athayde . Bittencourt . Maraya de Jesus Semblano . Miranda . Mario Fernando Ribeiro de . Carneiro . Francisca Regina Oliveira . Tufted angioma in ear auricle: importance of the differential diagnosis . Anais Brasileiros de Dermatologia . FapUNIFESP (SciELO) . 88 . 6 suppl 1 . 2013 . 0365-0596 . 10.1590/abd1806-4841.20132538 . 113–115.
  11. Kazlouskaya . Viktoryia . Lytvynenko . Bohdan . Blochin . Elen . Tufted hemangioma: clinical case and literature review . Dermatology Practical & Conceptual . Mattioli1885 . 2014-04-30 . 4 . 2 . 2160-9381 . 10.5826/dpc.0402a06 . 33–35. 24855571 . 4029251 .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Tufted angioma".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.