Tryptophan tryptophylquinone explained

Tryptophan tryptophylquinone (TTQ)^[1] is an enzyme cofactor, generated by posttranslational modification of amino acids within the protein. Methylamine dehydrogenase (MADH), an amine dehydrogenase, requires TTQ for its catalytic function.^[2]

See also

• Amicyanin

Notes and References

1. Tryptophan tryptophylquinone biosynthesis: A radical approach to posttranslational modification, by Victor L. Davidson1 and Aimin Liu2, on National Center for Biotechnology Information, U.S. National Library of Medicine, published 2012 Jan 28. doi: 10.1016/j.bbapap.2012.01.008. 2012. 3432176. Davidson. V. L.. Liu. A.. Biochimica et Biophysica Acta. 1824. 11. 1299–1305. 10.1016/j.bbapap.2012.01.008. 22314272.
2. Davidson VL, Liu A . Uncovering novel biochemistry in the mechanism of tryptophan tryptophylquinone cofactor biosynthesis . Curr. Opin. Chem. Biol. . 2009 . 13 . 4 . 469–474 . 10.1016/j.cbpa.2009.06.026 . 19648051 . 2749888 .