Tropodithietic acid explained

Tropodithietic acid is a tropolone derivative produced by the marine bacteria Phaeobacter piscinae, Phaeobacter inhibens and Phaeobacter gallaeciensis.^{[1] [2]} Its structure is composed by a dithiete moiety fused to tropone-2-carboxylic acid.

Notes and References

1. Rabe . Patrick . Klapschinski . Tim A . Brock . Nelson L . Citron . Christian A . D’Alvise . Paul . Gram . Lone . Dickschat . Jeroen S . Synthesis and bioactivity of analogues of the marine antibiotic tropodithietic acid . Beilstein Journal of Organic Chemistry . 6 August 2014 . 10 . 1796–1801 . 10.3762/bjoc.10.188. 25161739 . 4142847 .
2. Beyersmann . Paul G. . Tomasch . Jürgen . Son . Kwangmin . Stocker . Roman . Göker . Markus . Wagner-Döbler . Irene . Simon . Meinhard . Brinkhoff . Thorsten . Dual function of tropodithietic acid as antibiotic and signaling molecule in global gene regulation of the probiotic bacterium Phaeobacter inhibens . Scientific Reports . December 2017 . 7 . 1 . 730 . 10.1038/s41598-017-00784-7. 28389641 . 5429656 . 2017NatSR...7..730B .