Tropacocaine Explained

Tropacocaine (tropacaine, benzoylpseudotropine, pseudotropine benzoate, descarbomethoxycocaine) is a cocaine-related alkaloid[1] and a contaminant of street cocaine.[2]

Chemistry

Synthesis

It can be synthesized from tropine using the Mitsunobu reaction.[3]

See also

Notes and References

  1. 10.1039/CT9099501020. CXVI.?Relation between chemical constitution and physiological action in the tropeines. Part II. Journal of the Chemical Society, Transactions. 95. 1020–1032. 1909. Jowett . H. A. D. . Pyman . F. L. .
  2. Meyer EM, Potter LT, De Vane CL, Irwin I, MacKay SL, Miller R, Ruttenber AJ. Effects of benzoyltropine and tropacocaine on several cholinergic processes in the rat brain. The Journal of Pharmacology and Experimental Therapeutics. 254. 2. 584–90. August 1990. 1974643. 2021-01-14.
  3. Web site: https://www.seanmichaelragan.com/html/[2008-09-10_Cocaine_analog_in_two_steps_from_native_plant_material.shtml Cocaine analog in two steps from native plant material].