Trans,polycis-decaprenyl diphosphate synthase explained

Trans,polycis-decaprenyl diphosphate synthase
Ec Number:	2.5.1.86

(Rv2361c, (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate synthase) is an enzyme with systematic name (adding 7 isopentenyl units) .^{[1] [2] [3]} This enzyme catalyses the following chemical reaction

\rightleftharpoons 7 diphosphate + trans,octacis-decaprenyl diphosphate

The enzyme is involved in the biosynthesis of decaprenyl phosphate.

Notes and References

1. Kaur D, Brennan PJ, Crick DC . Decaprenyl diphosphate synthesis in Mycobacterium tuberculosis . Journal of Bacteriology . 186 . 22 . 7564–70 . November 2004 . 15516568 . 524883 . 10.1128/JB.186.22.7564-7570.2004 .
2. Wang W, Dong C, McNeil M, Kaur D, Mahapatra S, Crick DC, Naismith JH . The structural basis of chain length control in Rv1086 . Journal of Molecular Biology . 381 . 1 . 129–40 . August 2008 . 18597781 . 2527485 . 10.1016/j.jmb.2008.05.060 .
3. Crick DC, Schulbach MC, Zink EE, Macchia M, Barontini S, Besra GS, Brennan PJ . Polyprenyl phosphate biosynthesis in Mycobacterium tuberculosis and Mycobacterium smegmatis . Journal of Bacteriology . 182 . 20 . 5771–8 . October 2000 . 11004176 . 94699 . 10.1128/JB.182.20.5771-5778.2000 .