Thymoquinone Explained

Thymoquinone is a phytochemical compound found in the plant Nigella sativa. It is also found in select cultivated Monarda fistulosa plants which can be steam distilled to produce an essential oil.

It has been classified as a pan-assay interference compound, which binds indiscriminately to many proteins.^[1] It is under preliminary research to identify its possible biological properties.^{[2] [3] [4]}

See also

• Dithymoquinone, a dimer of thymoquinone
• 2,5-Dimethoxy-p-cymene

Notes and References

1. Baell JB . Feeling Nature's PAINS: Natural Products, Natural Product Drugs, and Pan Assay Interference Compounds (PAINS) . Journal of Natural Products . 79 . 3 . 616–28 . March 2016 . 26900761 . 10.1021/acs.jnatprod.5b00947 .
2. Farkhondeh T, Samarghandian S, Borji A . An overview on cardioprotective and anti-diabetic effects of thymoquinone . Asian Pacific Journal of Tropical Medicine . 10 . 9 . 849–854 . September 2017 . 29080612 . 10.1016/j.apjtm.2017.08.020 . free .
3. 3. Ali. Md Yousuf. Akter. Zakia. Mei. Zhiqiang. Zheng. Meiling. Tania. Mousumi. Khan. Md Asaduzzaman. February 2021. Thymoquinone in autoimmune diseases: Therapeutic potential and molecular mechanisms. Biomedicine & Pharmacotherapy. 134. 111157. 10.1016/j.biopha.2020.111157. 1950-6007. 33370631. 229714190. free.
4. Abdelrahim . Maen . Esmail . Abdullah . Al Saadi . Noor . Zsigmond . Eva . Al Najjar . Ebtesam . Bugazia . Doaa . Al-Rawi . Hadeel . Alsaadi . Ayat . Kaseb . Ahmed O. . Thymoquinone's Antiviral Effects: It is Time to be Proven in the Covid-19 Pandemic Era and its Omicron Variant Surge . Frontiers in Pharmacology . 5 April 2022 . 13 . 10.3389/fphar.2022.848676. free . 35462919 . 9022724 .