Thymidylate 5'-phosphatase explained

thymidylate 5′-phosphatase
Ec Number:	3.1.3.35
Cas Number:	9026-80-6
Go Code:	0050340

The enzyme thymidylate 5′-phosphatase (EC 3.1.3.35) catalyzes the reaction

thymidylate + H₂O

\rightleftharpoons thymidine + phosphate

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is thymidylate 5′-phosphohydrolase. Other names in common use include thymidylate 5′-nucleotidase, deoxythymidylate 5′-nucleotidase, thymidylate nucleotidase, deoxythymidylic 5′-nucleotidase, deoxythymidylate phosphohydrolase, and dTMPase.

References

• Aposhian HV, Tremblay GY . 1966 . Deoxythymidylate 5′-nucleotidase. Purification and properties of an enzyme found after infection of Bacillus subtilis with phage SP5C . J. Biol. Chem. . 241 . 5095 - 101 . 4958986 . 21 .