Threonic acid explained

Threonic acid is a sugar acid derived from threose. The -isomer is a metabolite of ascorbic acid (vitamin C).[1] One study suggested that because -threonate inhibits DKK1 expression in vitro, it may have potential in treatment of androgenic alopecia.[2]

Notes and References

  1. Annual Review of Nutrition . 6 . 365–406 . 1986 . 3015170 . 10.1146/annurev.nu.06.070186.002053 . The Biochemical Functions of Ascorbic Acid . S Englard and S Seifter.
  2. Kwack . M. H.. Ahn . J. S.. Kim . M. K.. Kim . J. C.. Sun. Y. K.. Preventable effect of L-threonate, an ascorbate metabolite, on androgen-driven balding via repression of dihydrotestosteroneinduced dickkopf-1 expression in human hair dermal papilla cells. 10.5483/BMBRep.2010.43.10.688. BMB Reports. 43. 10. 688–692. 2010. 21034532. free.

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