Thiol oxidase explained

thiol oxidase
Ec Number:	1.8.3.2
Cas Number:	9029-39-4
Go Code:	0016972

In enzymology, a thiol oxidase is an enzyme that catalyzes the chemical reaction

4 R'C(R)SH + O₂

\rightleftharpoons 2 R'C(R)S-S(R)CR' + 2 H₂O

Thus, the two substrates of this enzyme are R'C(R)SH and O₂, whereas its two products are R'C(R)S-S(R)CR' and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with oxygen as acceptor. The systematic name of this enzyme class is thiol:oxygen oxidoreductase. This enzyme is also called sulfhydryl oxidase.

References

• AURBACH GD, JAKOBY WB . 1962 . The multiple functions of thiooxidase . J. Biol. Chem. . 237 . 565 - 8 . 13863296 .
• NEUFELD HA, GREEN LF, LATTERELL FM, WEINTRAUB RL . 1958 . Thioxidase, a new sulfhydryl-oxidizing enzyme from Piricularia oryzae and Polyporus versicolor . J. Biol. Chem. . 232 . 1093 - 9 . 13549489 . 2 .