Thermospermine synthase explained

Thermospermine synthase
Ec Number:	2.5.1.79

Thermospermine synthase (TSPMS, ACL5 (ACAULIS5), SAC51) is an enzyme with systematic name S-adenosylmethioninamine:spermidine 3-aminopropyltransferase (thermospermine synthesizing).^{[1] [2] [3]} This enzyme catalyses the following chemical reaction

\rightleftharpoons S-methyl-5'-thioadenosine + thermospermine + H⁺

This enzyme is required for correct xylem specification through regulation of the lifetime of the xylem elements.

Notes and References

1. Romer P, Faltermeier A, Mertins V, Gedrange T, Mai R, Proff P . Investigations about N-aminopropyl transferases probably involved in biomineralization . Journal of Physiology and Pharmacology . 59 Suppl 5 . 27–37 . November 2008 . 19075322 .
2. Knott JM, Römer P, Sumper M . Putative spermine synthases from Thalassiosira pseudonana and Arabidopsis thaliana synthesize thermospermine rather than spermine . FEBS Letters . 581 . 16 . 3081–6 . June 2007 . 17560575 . 10.1016/j.febslet.2007.05.074 . free .
3. Muñiz L, Minguet EG, Singh SK, Pesquet E, Vera-Sirera F, Moreau-Courtois CL, Carbonell J, Blázquez MA, Tuominen H . ACAULIS5 controls Arabidopsis xylem specification through the prevention of premature cell death . Development . 135 . 15 . 2573–82 . August 2008 . 18599510 . 10.1242/dev.019349 . free .