Targeted lung denervation explained

Targeted lung denervation
Specialty:Pulmonology
Synonyms:TLD

Targeted lung denervation (TLD) is a procedure, that is currently being studied, to try to improve chronic obstructive pulmonary disease (COPD).[1] Evidence to support its use is insufficient as of 2015.[1] TLD is intended to block airway nerves of the parasympathetic nervous system to try to relax the airways.[2] The procedure is done using a balloon catheter through a bronchoscope and uses radio frequency energy. The bronchoscope is passed through the person's mouth and into their lungs. A dual-cooled radiofrequency ablation catheter is passed through the bronchoscope to provide the treatment.

Notes and References

  1. Gompelmann D, Eberhardt R, Herth FJ . Novel Endoscopic Approaches to Treating Chronic Obstructive Pulmonary Disease and Emphysema . Seminars in Respiratory and Critical Care Medicine . 36 . 4 . 609–15 . August 2015 . 26238645 . 10.1055/s-0035-1555614 . 9279526 .
  2. Belmont. Kristen E.. Nov 1, 2005. Cholinergic Pathways in the Lungs and Anticholinergic Therapy for Chronic Obstructive Pulmonary Disease. Proceedings of the American Thoracic Society. 2. 4. 297–304. 10.1513/pats.200504-043SR. 16267352.