Sulfoacetaldehyde dehydrogenase explained

Sulfoacetaldehyde dehydrogenase
Ec Number:	1.2.1.73

Sulfoacetaldehyde dehydrogenase (SafD) is an enzyme with systematic name 2-sulfoacetaldehyde:NAD⁺ oxidoreductase.^[1] This enzyme catalyses the following chemical reaction

2-sulfoacetaldehyde + H₂O + NAD⁺

\rightleftharpoons sulfoacetate + NADH + 2 H⁺

This reaction is part of a bacterial pathway that can make use the amino group of taurine as a sole source of nitrogen for growth.

Notes and References

1. Krejcík Z, Denger K, Weinitschke S, Hollemeyer K, Paces V, Cook AM, Smits TH . Sulfoacetate released during the assimilation of taurine-nitrogen by Neptuniibacter caesariensis: purification of sulfoacetaldehyde dehydrogenase . Archives of Microbiology . 190 . 2 . 159–68 . August 2008 . 18506422 . 10.1007/s00203-008-0386-2 .