Sulcatone reductase explained

sulcatone reductase
Ec Number:	1.1.1.260
Cas Number:	196522-54-0
Go Code:	0050491

In enzymology, a sulcatone reductase is an enzyme that catalyzes the chemical reaction

sulcatol + NAD⁺

\rightleftharpoons sulcatone + NADH + H⁺

Thus, the two substrates of this enzyme are sulcatol and NAD⁺, whereas its 3 products are sulcatone, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is sulcatol:NAD⁺ oxidoreductase.

References

• Belan A, Botle J, Fauve A, Gourcy JG, Veschambre H . 1987 . Use of biological systems for the preparation of chiral molecules 3. An application in pheromone synthesis: Preparation of sulcatol enantiomers . J. Org. Chem. . 52 . 256 - 260 . 10.1021/jo00378a017 . 2 .
• Tidswell EC, Salter GJ, Kell DB, Morris JG . 1997 . Enantioselectivity of sulcatone reduction by some anaerobic bacteria . Enzyme and Microbial Technology . 21 . 143 - 147 . 10.1016/S0141-0229(96)00264-5 . 2 .
• Tidswell EC, Thompson AN, Morris JG . 1991 . Selection in chemostat culture of a mutant strain of Clostridium tryobutyricum improved in its reduction of ketones . J. Appl. Microbiol. Biotechnol. . 35 . 317 - 322 .