Sucrose—1,6-alpha-glucan 3(6)-alpha-glucosyltransferase explained

sucrose-1,6-alpha-glucan 3(6)-alpha-glucosyltransferase
Ec Number:	2.4.1.125
Cas Number:	81725-87-3
Go Code:	0047217

In enzymology, a sucrose-1,6-alpha-glucan 3(6)-alpha-glucosyltransferase is an enzyme that catalyzes the chemical reaction

sucrose + (1,6-alpha-D-glucosyl)n

\rightleftharpoons D-fructose + (1,6-alpha-D-glucosyl)n⁺1

Thus, the two substrates of this enzyme are sucrose and (1,6-alpha-D-glucosyl)n, whereas its two products are D-fructose and (1,6-alpha-D-glucosyl)n+1.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is sucrose:1,6-alpha-D-glucan 3(6)-alpha-D-glucosyltransferase. Other names in common use include water-soluble-glucan synthase, GTF-S, sucrose-1,6-alpha-glucan 3(6)-alpha-glucosyltransferase, sucrose:1,6-alpha-D-glucan 3-alpha- and 6-alpha-glucosyltransferase, sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and, and 6-alpha-D-glucosyltransferase.

References

• Mukasa H, Shimamura A, Tsumori H . 1982 . Purification and characterization of basic glucosyltransferase from Streptococcus mutans serotype c . Biochim. Biophys. Acta . 719 . 81 - 9 . 6216919 . 1 . 10.1016/0304-4165(82)90310-5.
• Shimamura A, Tsumori H, Mukasa H . 1982 . Purification and properties of Streptococcus mutans extracellular glucosyltransferase . Biochim. Biophys. Acta . 702 . 72 - 80 . 6461359 . 1 . 10.1016/0167-4838(82)90028-0.
• Tsumori H, Shimamura A, Mukasa H . 1985 . Purification and properties of extracellular glucosyltransferase synthesizing 1,6-, 1,3-alpha-D-glucan from Streptococcus mutans serotype a . J. Gen. Microbiol. . 131 . 3347 - 53 . 2937877 . 12 . 10.1099/00221287-131-12-3347. free .