Strombine dehydrogenase explained

strombine dehydrogenase
Ec Number:	1.5.1.22
Cas Number:	79393-84-3
Go Code:	0050305

In enzymology, a strombine dehydrogenase is an enzyme that catalyzes the chemical reaction

N-(carboxymethyl)-D-alanine + NAD⁺ + H₂O

\rightleftharpoons glycine + pyruvate + NADH + H⁺

The 3 substrates of this enzyme are N-(carboxymethyl)-D-alanine, NAD⁺, and H₂O, whereas its 4 products are glycine, pyruvate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N-(carboxymethyl)-D-alanine:NAD+ oxidoreductase (glycine-forming). Other names in common use include strombine[N-(carboxymethyl)-D-alanine]dehydrogenase, and N-(carboxymethyl)-D-alanine: NAD+ oxidoreductase.

References

• Dando PR . 1981 . Strombine [N-(carboxymethyl)-D-alanine] dehydrogenase and alanopine [meso-N-(1-carboxyethyl)-alanine dehydrogenase from the mussel Mytilus edulis L | journal = Biochem. Soc. Trans. | volume = 9 | pages = 297–298 ].