Steganacin Explained

Steganacin is an dibenzocyclooctadiene lactone, an unusual type of lignan.[1] It exhibits some antileukemic properties in vitro.[2] It has been isolated from Steganotaenia araliacea.[2] (−)-Steganacin is the natural form.[3]

Notes and References

  1. 10.1023/B:PHYT.0000045487.02836.32. Diversity in lignan biosynthesis. 2003. Umezawa. Toshiaki. Phytochemistry Reviews. 2. 3. 371–390. 2003PChRv...2..371U . 6276953.
  2. Kupchan . SM . Britton . RW . Ziegler . MF . Gilmore . CJ . Restivo . RJ . Bryan . RF . Steganacin and steganangin, novel antileukemic lignan lactones from Steganotaenia araliacea. . Journal of the American Chemical Society . 21 February 1973 . 95 . 4 . 1335–6 . 10.1021/ja00785a054 . 4687687.
  3. Augros . David . Yalcouye . Boubacar . Choppin . Sabine . Chessé . Matthieu . Panossian . Armen . Leroux . Frédéric R. . Transition-Metal-Free Synthesis of a Known Intermediate in the Formal Synthesis of (-)-Steganacin: Transition-Metal-Free Synthesis of a Known Intermediate in the Formal Synthesis of (-)-Steganacin . European Journal of Organic Chemistry . 18 January 2017 . 2017 . 3 . 497–503 . 10.1002/ejoc.201601239. 100375916 .

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