Stearidonic acid explained

Stearidonic acid (SDA: C18H28O2; 18:4, n-3) is an ω-3 fatty acid, sometimes called moroctic acid.

Biosynthesis

It is biosynthesized from alpha-linolenic acid (ALA: C18H30O2; 18:3, n-3) by the enzyme delta-6-desaturase, which removes two hydrogen (H) atoms.

Stearidonic acid is a precursor to eicosapentaenoic acid.[1]

As it is a precursor to other fatty acids, there has been efforts to enhance the content off stearidonic acid in various crops, such as soybeans.[2]

SDA is also a precursor to N-acylethanolamine (NAEs).[3] [4] Natural sources of this fatty acid are the seed oils of hemp, blackcurrant, corn gromwell,[5] and Echium plantagineum, and the cyanobacterium Spirulina. SDA can also be synthesized in a lab. A GMO soybean source is approved by the European Food Safety Authority.[6]

See also

Notes and References

  1. 10.3945/jn.111.155259 . Mechanisms of Action of (N-3) Fatty Acids . 2012 . Calder . Philip C. . The Journal of Nutrition . 142 . 3 . 592S–599S . 22279140 . free .
  2. 10.3389/fnut.2018.00012. free . Biofortified Crops Generated by Breeding, Agronomy, and Transgenic Approaches Are Improving Lives of Millions of People around the World . 2018 . Garg . Monika . Sharma . Natasha . Sharma . Saloni . Kapoor . Payal . Kumar . Aman . Chunduri . Venkatesh . Arora . Priya . Frontiers in Nutrition . 5 . 12 . 29492405 . 5817065 .
  3. Galasso . Incoronata . Russo . Roberto . Mapelli . Sergio . Ponzoni . Elena . Brambilla . Ida M. . Battelli . Giovanna . Reggiani . Remo . 2016-05-20 . Variability in Seed Traits in a Collection of Cannabis sativa L. Genotypes . Frontiers in Plant Science . 7 . 688 . 10.3389/fpls.2016.00688 . 1664-462X . 4873519 . 27242881. free .
  4. Web site: PubChem . Stearidonic acid . 2022-11-22 . pubchem.ncbi.nlm.nih.gov . en.
  5. Web site: Corn Gromwell . https://web.archive.org/web/20110704143726/http://www.niab.com/pages/id/319/Corn_Gromwell . 2011-07-04 . NIAB.
  6. Web site: Scientific Opinion on genetically modified soybean MON 87769. 2014-05-16. European Food Safety Authority. en. 2019-02-18.

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