Sorbose 5-dehydrogenase (NADP+) explained

sorbose 5-dehydrogenase (NADP^+)
Ec Number:	1.1.1.123
Cas Number:	37250-52-5
Go Code:	0050287

In enzymology, a sorbose 5-dehydrogenase (NADP⁺) is an enzyme that catalyzes the chemical reaction

L-sorbose + NADP⁺

\rightleftharpoons 5-dehydro-D-fructose + NADPH + H⁺

Thus, the two substrates of this enzyme are L-sorbose and NADP⁺, whereas its 3 products are 5-dehydro-D-fructose, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is L-sorbose:NADP⁺ 5-oxidoreductase. Other names in common use include 5-ketofructose reductase, 5-keto-D-fructose reductase, sorbose (nicotinamide adenine dinucleotide phosphate) dehydrogenase, reduced nicotinamide adenine dinucleotide phosphate-linked, reductase, and sorbose 5-dehydrogenase (NADP⁺).

References

• Englard S, Kaysen G, Avigad G . 1970 . 5-keto-D-fructose. VI. A specific reduced nicotinamide adenine dinucleotide phosphate-linked reductase from yeast . J. Biol. Chem. . 245 . 1311–8 . 4392628 . 6 .