Asparagus racemosus explained

Asparagus racemosus (satavar, shatavari, or shatamull, shatawari) is a species of asparagus native from Africa through southern Asia, including the Indian subcontinent, to northern Australia.[1] [2] It grows NaNm (-2,147,483,648feet) tall and prefers to take root in gravelly, rocky soils high up in piedmont plains, at NaNm (-2,147,483,648feet) elevation.[3] It was botanically described in 1799. Because of its multiple uses, the demand for Asparagus racemosus is constantly on the rise. Due to destructive harvesting, combined with habitat destruction, and deforestation, the plant is now considered "endangered" in its natural habitat.

Description

Asparagus racemosus is a climber having stems up to 4 m long. Its roots are both fibrous and tuberous.

Shatavari has small pine-needle-like phylloclades (photosynthetic branches) that are uniform and shiny green. In July, it produces minute, white flowers on short, spiky stems, and in September it fruits, producing blackish-purple, globular berries. It has an adventitious root system with tuberous roots that measure about one metre in length, tapering at both ends, with roughly a hundred on each plant.

Uses

Shatavari is used in Indian traditional medicine.[4] [5] [6] Despite its long history of use in Ayurveda, no high-quality clinical evidence exists to support using shatavari as a therapy for any disease.[4] Studies of its effects on lactation have shown mixed results.[7] Its safety has not been well-studied, with two small trials finding no adverse effects in mothers or their babies.[7] Constituents of shatavari include steroidal saponins, mucilage, and alkaloids.[7]

Australian aboriginal uses

The roots of Asparagus racemosus are boiled and give a liquid used as an external wash to treat colds and other sicknesses, by the aborigines of the Moyle River area in the Northern Territory.[8] (The Ngan'gi name for the plant is yerrwuwu.)

Chemical constituents

Asparagamine A, a polycyclic alkaloid was isolated from the dried roots[9] [10] and subsequently synthesized to allow for the construction of analogs.[11]

Steroidal saponins, shatavaroside A, shatavaroside B, filiasparoside C, shatavarins, immunoside, and schidigerasaponin D5 (or asparanin A) were isolated from the roots of Asparagus racemosus.[12] [13]

Also known is the isoflavone 8-methoxy-5,6,4'-trihydroxyisoflavone 7-O-β-D-glucopyranoside.[14]

See also

External links

Notes and References

  1. Web site: Asparagus racemosus Willd.. . Plants of the World Online . Royal Botanic Gardens, Kew. 2023-01-12 .
  2. Book: H. T. Clifford, J. G. Conran. Flora of Australia. Australian Biological Resources Study, Department of Agriculture, Water and the Environment. 2020. Canberra. Asparagus racemosus. 2021-03-21. https://profiles.ala.org.au/opus/foa/profile/Asparagus%20racemosus.
  3. Web site: LILIACEAE – Famine Foods . Robert Freeman . Centre for New Crops and Plant Products, Department of Horticulture & Landscape Architecture . . February 26, 1998 . April 25, 2009.
  4. Book: Pizzorno Jr. . Joseph E. . Murray . Michael T. . Joiner-Bey . Herb . The Clinician's Handbook of Natural Medicine . 2015 . Churchill Livingstone . 9780702055140 . 516 . 3rd.
  5. Book: Hechtman . Leah . Clinical Naturopathic Medicine . 2018 . Elsevier . 9780729542425 . 879, 908 . 2.
  6. Goyal . R. K. . Singh . Janardhan . Lal . Harbans . Asparagus racemosus—an update . Indian Journal of Medical Sciences . September 2003 . 57 . 9 . 408–414 . 14515032.
  7. Wild asparagus . LactMed . National Library of Medicine, US National Institutes of Health . 31 March 2022. 16 August 2021. 30000872. en.
  8. 166.
  9. http://leygroup.ch.cam.ac.uk/lab_letters/PDF/asparagamine.pdf The Ley Group: Combinatorial Chemistry and total synthesis of natural products
  10. 10.1002/chin.199505264 . 26 . 5 . no . ChemInform Abstract: Structure of Asparagamine A (I), a Novel Polycyclic Alkaloid from Asparagus racemosus . 2010 . ChemInform . Sekine . T..
  11. http://www.researchgrantdatabase.com/g/1F32CA091635-01/Total-Synthesis-of-the-Antitumor-Agent-Asparagamine-A/ Total Synthesis Of The Antitumor Agent Asparagamine A
  12. 19652422. 2009. Sharma. U. Steroidal saponins from Asparagus racemosus. Chemical & Pharmaceutical Bulletin. 57. 8. 890–3. Saini. R. Kumar. N. Singh. B. 10.1248/cpb.57.890. free.
  13. 10.1016/j.phytochem.2007.09.001. 17936315. Steroidal saponins from the roots of Asparagus racemosus. Phytochemistry. 69. 3. 796–804. 2008. Hayes. Patricia Y.. Jahidin. Aisyah H.. Lehmann. Reg. Penman. Kerry. Kitching. William. De Voss. James J.. 2008PChem..69..796H.
  14. 11295314. 2001. Saxena. V. K.. A new isoflavone from the roots of Asparagus racemosus. Fitoterapia. 72. 3. 307–9. Chourasia. S. 10.1016/s0367-326x(00)00315-4.

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