Semenogelase Explained

Semenogelase
Ec Number:3.4.21.77
Cas Number:110157-83-0, 95829-41-7

Semenogelase (prostate-specific antigen, alpha-seminoprotein, seminin, P-30 antigen, antigen (human clone HPSA-1 prostate-specific protein moiety reduced), gamma-seminoglycoprotein (human protein moiety reduced), gamma-SM, antigen PSA (human prostate-specific), human glandular kallikrein, antigen PSA (human clone 5P1 protein moiety reduced)) is an enzyme.[1] [2] This enzyme catalyses the following chemical reaction

Preferential cleavage: -Tyr-

This peptidase from trypsin family is present in seminal plasma.

See also

Notes and References

  1. Digby M, Zhang XY, Richards RI . Human prostate specific antigen (PSA) gene: structure and linkage to the kallikrein-like gene, hGK-1 . Nucleic Acids Research . 17 . 5 . 2137 . March 1989 . 2467258 . 317563 . 10.1093/nar/17.5.2137 .
  2. Christensson A, Laurell CB, Lilja H . Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors . European Journal of Biochemistry . 194 . 3 . 755–63 . December 1990 . 1702714 . 10.1111/j.1432-1033.1990.tb19466.x . free .