Segesterone Explained

Segesterone,[1] [2] also known as 17α-hydroxy-16-methylene-19-norprogesterone or as 17α-deacetylnestorone, is a steroidal progestin of the 19-norprogesterone group that was never marketed.[3] An acetate ester, segesterone acetate, better known as nestorone or elcometrine, is marketed for clinical use.[4] Segesterone acetate produces segesterone as a metabolite.[5]

Notes and References

  1. International Nonproprietary Names for Pharmaceutical Substances (INN) . . 2003 . 17 . 210 . https://web.archive.org/web/20220120170245/https://www.who.int/medicines/publications/druginformation/innlists/PL89.pdf . 2022-01-20 . 3.
  2. Web site: 7690-08-6 - SFLXYFZGKSGFKA-XUDSTZEESA-N - Segesterone [USAN:INN] - Similar structures search, synonyms, formulas, resource links, and other chemical information . ChemIDplus . U.S. National Library of Medicine . 2016-06-17 . 2016-08-11 . https://web.archive.org/web/20160811090659/https://chem.nlm.nih.gov/chemidplus/rn/7690-08-6 . dead .
  3. Web site: Segesterone . PubChem . U.S. National Library of Medicine .
  4. Book: Zavod RM . Chapter 41: Women's Health . Lemke TL, Williams DA . Foye's Principles of Medicinal Chemistry. https://books.google.com/books?id=Sd6ot9ul-bUC&pg=PA1403. 24 January 2012. Lippincott Williams & Wilkins. 978-1-60913-345-0. 1403–.
  5. Prasad PV, Bashir M, Sitruk-Ware R, Kumar N . Single-dose pharmacokinetics of Nestorone, a potential female-contraceptive . Steroids . 75 . 3 . 252–264 . March 2010 . 20064539 . 10.1016/j.steroids.2009.12.011 . 205253216 .

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