Scymnol sulfotransferase explained

Scymnol sulfotransferase
Ec Number:	2.8.2.32

In enzymology, a scymnol sulfotransferase is an enzyme that catalyzes the chemical reaction

3'-Phosphoadenosine-5'-phosphosulfate + 5beta-scymnol

\rightleftharpoons adenosine 3',5'-bisphosphate + 5beta-scymnol sulfate

Thus, the two substrates of this enzyme are 3'-Phosphoadenosine-5'-phosphosulfate and 5Beta-Scymnol, whereas its two products are adenosine 3',5'-bisphosphate and 5beta-scymnol sulfate.

This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-Phosphoadenosine-5'-phosphosulfate:5beta-scymnol sulfotransferase.

References

• Macrides TA, Faktor DA, Kalafatis N, Amiet RG . 1994 . Enzymic sulfation of bile salts. Partial purification and characterization of an enzyme from the liver of the shark Heterodontus portusjacksoni that catalyses the sulfation of the shark bile steroid 5 beta-scymnol . Comp. Biochem. Physiol. B . 107 . 461 - 9 . 7749614 . 10.1016/0305-0491(94)90212-7 . 3 .
• Pettigrew NE, Wright PF, Macrides TA . 1998 . Investigation of 5beta-scymnol sulfotransferase from the kidney and testes of Heterodontus portusjacksoni . Comp. Biochem. Physiol. . 121 . 243 - 249 .
• Pettigrew NE, Wright PF, Macrides TA . 1998 . 5beta-Scymnol sulfotransferase isolated from the tissues of an Australian shark species . Comp. Biochem. Physiol. . 121 . 299 - 307 .
• Pettigrew NE, Wright PF, Macrides TA . 1998 . 5beta-scymnol sulfotransferase isolated from the liver of two Australian ray species . Comp. Biochem. Physiol. . 121 . 341 - 348 .