Salicylaldehyde dehydrogenase explained

salicylaldehyde dehydrogenase
Ec Number:	1.2.1.65
Go Code:	0018485

In enzymology, a salicylaldehyde dehydrogenase is an enzyme that catalyzes the chemical reaction

salicylaldehyde + NAD⁺ + H₂O

\rightleftharpoons salicylate + NADH + 2 H⁺

The 3 substrates of this enzyme are salicylaldehyde, NAD⁺, and H₂O, whereas its 3 products are salicylate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is salicylaldehyde:NAD+ oxidoreductase. This enzyme participates in naphthalene and anthracene degradation.

References

• Eaton RW, Chapman PJ . 1992 . Bacterial metabolism of naphthalene: construction and use of recombinant bacteria to study ring cleavage of 1,2-dihydroxynaphthalene and subsequent reactions . J. Bacteriol. . 174 . 7542 - 54 . 1447127 . 23 . 207464 .