Ryanoids are a class of insecticides which share the same mechanism of action as the alkaloid ryanodine. Ryanodine is a naturally occurring insecticide isolated from Ryania speciosa.
Ryanoids include natural chemicals which are closely related to ryanodine, such as ryanodol and 9,21-didehydroryanodol,[1] and also chemically distinct synthetic compounds such as chlorantraniliprole (Rynaxypyr), flubendiamide, cyantraniliprole, cyclaniliprole, and tetraniliprole (Tetrino), which are called diamide insecticides.[2]
Ryanoids exert their insecticidal effect by interacting with ryanodine receptors, a type of calcium channel. This causes loss of muscle function leading to paralysis and death.