Rs28363170 Explained

Rsid:	28363170
Chromosome:	5

In genetics, rs28363170 (DAT1-VNTR) is a genetic variation at SLC6A3, the gene that encodes the dopamine transporter. It is polymorphism as a 40 base pairs VNTR in the 3' untranslated region.It is a deletion/insertion polymorphism (DIP).^[1]

The 9-repeat and the 10-repeat are the most common alleles.^[2]

References

Further

• A 40-nucleotide repeat polymorphism in the human dopamine transporter gene . . 91 . 4 . 405–406 . May 1993 . 8500798 . 10.1007/BF00217369 . A. Sano. K. Kondoh. Y. Kakimoto . 39416578 . A. Sano . K. Kondoh . Y. Kakimoto .
• 10.1038/sj.npp.1301240 . 2007 . Grizenko . N . Sengupta . S . Amor . LB . Schmitz . N . Schwartz . G . Karama . S . Lageix . P . Fathalli . F . Torkaman-Zehi . Adam . Stepanian . Marina Ter . Dopamine transporter 3'-UTR VNTR genotype and ADHD: a pharmaco-behavioural genetic study with methylphenidate . Neuropsychopharmacology . 32 . 6 . 1370–1376 . 17063150. 8 . Joober . R. . 2944059 .

Notes and References

1. Web site: Rs28363170 RefSNP Report - DBSNP - NCBI.
2. Book: David Mrazek . Psychiatric Pharmacogenomics . . 2010. David Mrazek .