Ribostamycin:4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoyl-(BtrI acyl-carrier protein) 4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoate transferase explained

Ribostamycin:4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoyl-(BtrI acyl-carrier protein) 4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoate transferase
Ec Number:2.3.2.19

Ribostamycin:4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoyl-(BtrI acyl-carrier protein) 4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoate transferase (btrH (gene)) is an enzyme with systematic name ribostamycin:4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoyl-(BtrI acyl-carrier protein) 4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoate transferase.[1] This enzyme catalyses the following chemical reaction

\rightleftharpoons

gamma-L-glutamyl-butirosin B + BtrI acyl-carrier protein

The enzyme attaches the side chain of the aminoglycoside antibiotics of the butirosin family.

Notes and References

  1. Llewellyn NM, Li Y, Spencer JB . Biosynthesis of butirosin: transfer and deprotection of the unique amino acid side chain . Chemistry & Biology . 14 . 4 . 379–86 . April 2007 . 17462573 . 10.1016/j.chembiol.2007.02.005 .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Ribostamycin:4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoyl-(BtrI acyl-carrier protein) 4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoate transferase".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.