Ribonuclease T2 Explained

Ribonuclease T2
Ec Number:	3.1.27.1
Cas Number:	37278-25-4

Ribonuclease T2 (acid ribonuclease, acid RNase, base-non-specific ribonuclease, Escherichia coli ribonuclease I' ribonuclease PP2, Escherichia coli ribonuclease II, non-base specific ribonuclease, nonbase-specific RNase, nonspecific RNase, ribonnuclease (non-base specific), ribonuclease (non-base specific), ribonuclease II, ribonuclease M, ribonuclease N2, ribonuclease PP3, ribonuclease U4, ribonucleate 3'-oligonucleotide hydrolase, ribonucleate nucleotido-2'-transferase (cyclizing), RNAase CL, RNase (non-base specific), RNase II, RNase M, RNase Ms, RNase T2,) is an enzyme.^{[1] [2] [3] [4]} It is a type of endoribonuclease. This enzyme catalyses the following chemical reaction

Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates

See also

• RNASET2

Notes and References

1. García-Segura JM, Orozco MM, Fominaya JM, Gavilanes JG . Purification, molecular and enzymic characterization of an acid RNase from the insect Ceratitis capitata . European Journal of Biochemistry . 158 . 2 . 367–72 . July 1986 . 3732273 . 10.1111/j.1432-1033.1986.tb09760.x .
2. Book: Pig liver nuclei ribonuclease . Procedures in Nucleic Acid Research . Heppel LA, Davies DR . 1966 . 31–36 . Cantoni GL . Procedures in Nucleic Acid Research . New York .
3. Reddi KK, Mauser LJ . Studies on the formation of tobacco mosaic virus ribonucleic acid. VI. Mode of degradation of host ribonucleic acid to ribonucleosides and their conversion to ribonucleoside 5-phosphates . Proceedings of the National Academy of Sciences of the United States of America . 53 . 3 . 607–13 . March 1965 . 14338240 . 336984 . 10.1073/pnas.53.3.607 . free .
4. Uchida T, Egami F . The specificity of ribonuclease T2 . Journal of Biochemistry . 61 . 1 . 44–53 . January 1967 . 10.1093/oxfordjournals.jbchem.a128519 . 6048969 .