Ribonuclease M5 Explained

Ribonuclease M5
Ec Number:	3.1.26.8
Cas Number:	62253-00-3

Ribonuclease M5 (RNase M5, 5S ribosomal maturation nuclease, 5S ribosomal RNA maturation endonuclease) is an enzyme.^[1] This enzyme catalyses the following chemical reaction

Endonucleolytic cleavage of RNA, removing 21 and 42 nucleotides, respectively, from the 5'- and 3'-termini of a 5S-rRNA precursor

This enzyme converts the 5S-rRNA precursor from Bacillus subtilis into 5S-rRNA.

Notes and References

1. Sogin ML, Pace B, Pace NR . Partial purification and properties of a ribosomal RNA maturation endonuclease from Bacillus subtilis . The Journal of Biological Chemistry . 252 . 4 . 1350–7 . February 1977 . 402365 .