Ribitol 2-dehydrogenase explained

ribitol 2-dehydrogenase
Ec Number:1.1.1.56
Cas Number:9014-23-7
Go Code:0050255

In enzymology, a ribitol 2-dehydrogenase is an enzyme that catalyzes the chemical reaction

ribitol + NAD+

\rightleftharpoons

D-ribulose + NADH + H+

Thus, the two substrates of this enzyme are ribitol and NAD+, whereas its 3 products are D-ribulose, NADH, and H+.

This enzyme participates in pentose and glucuronate interconversions.

Nomenclature

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is ribitol:NAD+ 2-oxidoreductase. Other names in common use include adonitol dehydrogenase, ribitol dehydrogenase A (wild type), ribitol dehydrogenase B (mutant enzyme with different properties), and ribitol dehydrogenase D (mutant enzyme with different properties).

References