Respirovirus Explained

Respirovirus is a genus of viruses in the order Mononegavirales, in the family Paramyxoviridae.[1] Rodents and human serve as natural hosts. There are seven species in this genus.[2] Diseases associated with this genus include: croup and other acute febrile respiratory tract infections.[3]

Structure

Respirovirions are enveloped, with spherical geometries. The diameter is around 150 nm. Respirovirus genomes are linear, around 15kb in length. The genome codes for 8 proteins.

Genus Structure Symmetry !Capsid Genomic arrangement Genomic segmentation
RespirovirusSphericalEnvelopedLinearMonopartite

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by virus attaches to host cell. Replication follows the negative stranded RNA virus replication model. Negative stranded RNA virus transcription, using polymerase stuttering is the method of transcription. Translation takes place by leaky scanning, and ribosomal shunting. The virus exits the host cell by budding. Rodents and human serve as the natural host. Transmission routes are respiratory.

External links

Notes and References

  1. Rima . B . Balkema-Buschmann . A . Dundon . WG . Duprex . WP. William Paul Duprex . Easton . A . Fouchier . R . Kurath . G . Lamb . R . Lee . B . Rota . P . Wang . L . ICTV Report Consortium . ICTV Virus Taxonomy Profile: Paramyxoviridae. . The Journal of General Virology . December 2019 . 100 . 12 . 1593–1594 . 10.1099/jgv.0.001328 . 31609197. free . 7273325 .
  2. Web site: Virus Taxonomy: 2020 Release . International Committee on Taxonomy of Viruses (ICTV) . March 2021 . 18 May 2021.
  3. Web site: Viral Zone. ExPASy. 15 June 2015.