Ravuconazole Explained
Ravuconazole (codenamed BMS-207147 and ER-30346) is a potent triazole antifungal, the development of which was discontinued in 2007.[1] The drug has shown to have a similar spectrum of activity to voriconazole, with an increased half-life.[2] However, ravuconazole has limited activity against species of Fusarium, Scedosporium, and Zygomycetes.[3] [4]
See also
Notes and References
- Web site: Ravuconazole. AdisInsight . Springer Nature Switzerland AG . 12 November 2017. en.
- Web site: Ravuconazole . The Aspergillus Website . Pasqualotto AC, Denning DW . 18 February 2010 .
- Pasqualotto AC, Thiele KO, Goldani LZ . Novel triazole antifungal drugs: focus on isavuconazole, ravuconazole and albaconazole . Current Opinion in Investigational Drugs . 11 . 2 . 165–174 . February 2010 . 20112166 .
- Pfaller MA, Messer SA, Hollis RJ, Jones RN . Antifungal activities of posaconazole, ravuconazole, and voriconazole compared to those of itraconazole and amphotericin B against 239 clinical isolates of Aspergillus spp. and other filamentous fungi: report from SENTRY Antimicrobial Surveillance Program, 2000 . Antimicrobial Agents and Chemotherapy . 46 . 4 . 1032–1037 . April 2002 . 11897586 . 127116 . 10.1128/AAC.46.4.1032-1037.2002 .