Quinaldate 4-oxidoreductase explained

quinaldate 4-oxidoreductase
Ec Number:	1.3.99.18
Cas Number:	149885-77-8
Go Code:	0047122

In enzymology, a quinaldate 4-oxidoreductase is an enzyme that catalyzes the chemical reaction

quinaldate + acceptor + H₂O

\rightleftharpoons kynurenate + reduced acceptor

The 3 substrates of this enzyme are quinaldate, acceptor, and H₂O, whereas its two products are kynurenate and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is quinoline-2-carboxylate:acceptor 4-oxidoreductase (hydroxylating). This enzyme is also called quinaldic acid 4-oxidoreductase.

References

• Sauter M, Tshisuaka B, Fetzner S, Lingens F . 1993 . Microbial metabolism of quinoline and related compounds. XX Quinaldic acid 4-oxidoreductase from Pseudomonas sp. AK-2 compared to other procaryotic molybdenum-containing hydroxylases . Biol. Chem. Hoppe-Seyler . 374 . 1037 - 46 . 8292263 . 11 . 10.1515/bchm3.1993.374.7-12.1037 .
• Fetzner S, Lingens F . 1993 . Microbial metabolism of quinoline and related compounds. XVIII Purification and some properties of the molybdenum- and iron-containing quinaldic acid 4-oxidoreductase from Serratia marcescens 2CC-1 . Biol. Chem. Hoppe-Seyler . 374 . 363 - 76 . 8357532 . 6 . 10.1515/bchm3.1993.374.1-6.363 .