Quercetin 3-O-methyltransferase explained
| quercetin 3-O-methyltransferase |
| Ec Number: | 2.1.1.76 |
| Cas Number: | 75603-21-3 |
| Go Code: | 0030755 |
In enzymology, a quercetin 3-O-methyltransferase is an enzyme that catalyzes the chemical reaction
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone
S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone
Thus, the two substrates of this enzyme are S-adenosyl methionine and 3,5,7,3',4'-pentahydroxyflavone, whereas its two products are S-adenosylhomocysteine and 3-methoxy-5,7,3',4'-tetrahydroxyflavone.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase. Other names in common use include flavonol 3-O-methyltransferase, and flavonoid 3-methyltransferase. This enzyme participates in flavonoid biosynthesis.
References
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- De Luca V, Ibrahim RK . 1985 . Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. I. Partial purification and some properties of S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and 4'-O-methyltransferases . Arch. Biochem. Biophys. . 238 . 596 - 605 . 3994393 . 10.1016/0003-9861(85)90205-X . 2 .
- De Luca V, Ibrahim RK . 1985 . Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. II. Substrate interaction and product inhibition studies of flavonol 3-, 6-, and 4'-O-methyltransferases . Arch. Biochem. Biophys. . 238 . 606 - 18 . 3994394 . 10.1016/0003-9861(85)90206-1 . 2 .
- Ibrahim RK . De Luca V . 1982 . Polymethylated flavonol synthesis is catalyzed by distinct O-methyltransferases . Naturwissenschaften . 69 . 1 . 41 - 42 . 10.1007/BF00441101 .
