Pulmonary atypical adenomatous hyperplasia explained

Atypical adenomatous hyperplasia (AAH) is a hyperplastic lesion of the epithelial lining of pulmonary alveoli.

Tumorigenesis

A multi-step carcinogenesis hypothesis suggests a progression from atypical adenomatous hyperplasia (AAH) through bronchioalveolar carcinoma (BAC) to invasive adenocarcinoma (AC), but to date this has not been formally demonstrated.[1]

Notes and References

  1. 23226769. 2012. Bettio. D. Cytogenetic findings in lung cancer that illuminate its biological history from adenomatous hyperplasia to bronchioalveolar carcinoma to adenocarcinoma: A case report. Experimental and Therapeutic Medicine. 4. 6. 1032–1034. Cariboni. U. Venci. A. Valente. M. Spaggiari. P. Alloisio. M. 10.3892/etm.2012.725. 3494121.

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