Pseudooxynicotine oxidase explained

Pseudooxynicotine oxidase
Ec Number:1.4.3.24

Pseudooxynicotine oxidase is an enzyme with systematic name 4-(methylamino)-1-(pyridin-3-yl)butan-1-one:oxygen oxidoreductase (methylamine releasing).[1] This enzyme catalyses the following chemical reaction

4-(methylamino)-1-(pyridin-3-yl)butan-1-one + H2O + O2

\rightleftharpoons

4-oxo-4-(pyridin-3-yl)butanal + methylamine + H2O2

This enzyme contains one non-covalently bound FAD.

Notes and References

  1. Qiu J, Ma Y, Wen Y, Chen L, Wu L, Liu W . Functional identification of two novel genes from Pseudomonas sp. strain HZN6 involved in the catabolism of nicotine . Applied and Environmental Microbiology . 78 . 7 . 2154–60 . April 2012 . 22267672 . 3302611 . 10.1128/AEM.07025-11 .

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