Protein-glucosylgalactosylhydroxylysine glucosidase explained
| protein-glucosylgalactosylhydroxylysine glucosidase |
| Ec Number: | 3.2.1.107 |
| Cas Number: | 72829-45-9 |
| Go Code: | 0047402 |
The enzyme protein-glucosylgalactosylhydroxylysine glucosidase catalyzes the following chemical reaction:
[collagen]-(5R)-5-O-[α-<small>D</small>-glucosyl-(1→2)-β-<small>D</small>-galactosyl]-5-hydroxy-L-lysine + H2O = D-glucose + [collagen]-(5R)-5-O-(β-D-galactosyl)-5-hydroxy-L-lysine
It belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name is protein-α-D-glucosyl-1,2-β-D-galactosyl-L-hydroxylysine glucohydrolase. Other names in common use include 2-O-α-D-glucopyranosyl-5-O-α-D-galactopyranosylhydroxy-L-lysine glucohydrolase, and lysine glucohydrolase.
References
- Hamazaki H, Hotta K . 1979 . Purification and characterization of an α-glucosidase specific for hydroxylysine-linked disaccharide of collagen . J. Biol. Chem. . 254 . 9682 - 7 . 385589 . 19 .
- Hamazaki H, Hotta K . 1980 . Enzymatic hydrolysis of disaccharide unit of collagen. Isolation of 2-O-α-D-glucopyranosyl-O-β-D-galactopyranosyl-hydroxylysine glucohydrolase from rat spleens . Eur. J. Biochem. . 111 . 587 - 91 . 7460918 . 10.1111/j.1432-1033.1980.tb04975.x . 2 . free .
- Sternberg M, Spiro RG . 1979 . Studies on the catabolism of the hydroxylysine-linked disaccharide units of basement membranes and collagens. Isolation and characterization of a rat kidney α-glucosidase of high specificity . J. Biol. Chem. . 254 . 10329 - 36 . 385599 . 20 .
