Prolyl aminopeptidase explained
| Prolyl aminopeptidase |
| Ec Number: | 3.4.11.5 |
| Cas Number: | 9025-40-5 |
Prolyl aminopeptidase (proline aminopeptidase, Pro-X aminopeptidase, cytosol aminopeptidase V, proline iminopeptidase) is an enzyme.[1] [2] [3] This enzyme catalyses the following chemical reaction
Release of N-terminal proline from a peptide
This enzyme requires Mn2+ ion to function.
Notes and References
- Sarid S, Berger A, Katchalski E . Proline iminopeptidase. II. Purification and comparison with iminodipeptidase (prolinase) . The Journal of Biological Chemistry . 237 . 2207–12 . July 1962 . 7 . 10.1016/S0021-9258(19)63420-4 . 14497218 . free .
- Nordwig A, Mayer H . The cleavage of prolyl peptides by kidney peptidases. Detection of a new peptidase capable of removing N-terminal proline . Hoppe-Seyler's Zeitschrift für Physiologische Chemie . 354 . 4 . 380–3 . April 1973 . 4803482 . 10.1515/bchm2.1973.354.1.380 .
- Turzynski A, Mentlein R . Prolyl aminopeptidase from rat brain and kidney. Action on peptides and identification as leucyl aminopeptidase . European Journal of Biochemistry . 190 . 3 . 509–15 . July 1990 . 2373079 . 10.1111/j.1432-1033.1990.tb15603.x . free .
